Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Exploratory Grants (P20)
Project #
5P20NS032570-03
Application #
2270855
Study Section
Special Emphasis Panel (SRC (20))
Project Start
1993-09-30
Project End
1997-08-31
Budget Start
1995-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
Tsuji, M; Saul, J P; du Plessis, A et al. (2000) Cerebral intravascular oxygenation correlates with mean arterial pressure in critically ill premature infants. Pediatrics 106:625-32
Rosenberg, P A; Li, Y; Ali, S et al. (1999) Intracellular redox state determines whether nitric oxide is toxic or protective to rat oligodendrocytes in culture. J Neurochem 73:476-84
Tsuji, M; duPlessis, A; Taylor, G et al. (1998) Near infrared spectroscopy detects cerebral ischemia during hypotension in piglets. Pediatr Res 44:591-5
Chen, H S; Wang, Y F; Rayudu, P V et al. (1998) Neuroprotective concentrations of the N-methyl-D-aspartate open-channel blocker memantine are effective without cytoplasmic vacuolation following post-ischemic administration and do not block maze learning or long-term potentiation. Neuroscience 86:1121-32
Back, S A; Gan, X; Li, Y et al. (1998) Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by glutathione depletion. J Neurosci 18:6241-53
Jensen, F E; Wang, C; Stafstrom, C E et al. (1998) Acute and chronic increases in excitability in rat hippocampal slices after perinatal hypoxia In vivo. J Neurophysiol 79:73-81
du Plessis, A J; Jonas, R A; Wypij, D et al. (1997) Perioperative effects of alpha-stat versus pH-stat strategies for deep hypothermic cardiopulmonary bypass in infants. J Thorac Cardiovasc Surg 114:991-1000; discussion 1000-1
Jonas, R A (1996) Hypothermia, circulatory arrest, and the pediatric brain. J Cardiothorac Vasc Anesth 10:66-74
Nomura, F; Naruse, H; duPlessis, A et al. (1996) Cerebral oxygenation measured by near infrared spectroscopy during cardiopulmonary bypass and deep hypothermic circulatory arrest in piglets. Pediatr Res 40:790-6
Yonezawa, M; Back, S A; Gan, X et al. (1996) Cystine deprivation induces oligodendroglial death: rescue by free radical scavengers and by a diffusible glial factor. J Neurochem 67:566-73

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