As a part of the USC Alzheimer Disease Research Center competitive renewal, the Imaging Core will continue to serve the overall mission to provide high-quality MR and PET imaging resources to the local and broader AD research community. The ADRC Imaging Core will provide core resources, including MR physics and PET expertise, multi-scanner sequence and protocol development, image data quality control and management, research collaboration, and a global framework for conducting AD neuroimaging research. The Imaging Core is led by a well-integrated and collaborative team, including Arthur Toga (Core Leader), Judy Pa (Core Co-Leader), Meredith Braskie, Danny JJ Wang, Nasim Sheikh-Bahaei, and Paul Thompson, who together provide expertise in vascular, functional, and structural imaging and its analyses for 3T and 7T MRI, and PET. We propose 5 specific aims that provide an imaging framework for all ADRC projects; perform high quality control of all imaging data; develop technical and scientific approaches for ultra- high field 7T MRI; assist in PET protocol development and quality control; and conduct education and training in modern imaging techniques. Taken together, these goals will serve the USC ADRC?s unifying scientific theme of vascular contributions to Alzheimer disease: risk factors, neurovascular and metabolic mechanisms, and risk reduction.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Center Core Grants (P30)
Project #
1P30AG066530-01
Application #
9922633
Study Section
Special Emphasis Panel (ZAG1)
Project Start
2020-09-01
Project End
2025-02-28
Budget Start
2020-04-01
Budget End
2021-03-31
Support Year
1
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Southern California
Department
Type
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90089