Abstract

This application is submitted as a supplement to the Johns Hopkins Oncology Center Support Grant (CA 06973A), for the purpose of enhancing the capabilities of the cell sorting facility already existing within the Center. Specifically, we are requesting funding for the following items of equipment: 1. A correlated, two-parameter data acquisition and display module, and expanded memory for the pulse-height analyzer of our FACS-II unit. 2. A data analysis system for local on-line data analysis, hard-copy output, and long-term data storage. 3. A cloning device to allow sorting of individual cells into specific wells of micro-titre plates.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA006973-26
Application #
3101230
Study Section
(SRC)
Project Start
1978-01-01
Project End
1991-04-30
Budget Start
1988-05-01
Budget End
1989-04-30
Support Year
26
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Paller, Channing J; Zhou, Xian C; Heath, Elisabeth I et al. (2018) Muscadine Grape Skin Extract (MPX) in Men with Biochemically Recurrent Prostate Cancer: A Randomized, Multicenter, Placebo-Controlled Clinical Trial. Clin Cancer Res 24:306-315
Fackler, Mary Jo; Sukumar, Saraswati (2018) Quantitation of DNA Methylation by Quantitative Multiplex Methylation-Specific PCR (QM-MSP) Assay. Methods Mol Biol 1708:473-496
Converse, Paul J; Almeida, Deepak V; Tasneen, Rokeya et al. (2018) Shorter-course treatment for Mycobacterium ulcerans disease with high-dose rifamycins and clofazimine in a mouse model of Buruli ulcer. PLoS Negl Trop Dis 12:e0006728
Tolbert, Elliott; Brundage, Michael; Bantug, Elissa et al. (2018) Picture This: Presenting Longitudinal Patient-Reported Outcome Research Study Results to Patients. Med Decis Making 38:994-1005
Newitt, David C; Malyarenko, Dariya; Chenevert, Thomas L et al. (2018) Multisite concordance of apparent diffusion coefficient measurements across the NCI Quantitative Imaging Network. J Med Imaging (Bellingham) 5:011003
Cottrell, T R; Thompson, E D; Forde, P M et al. (2018) Pathologic features of response to neoadjuvant anti-PD-1 in resected non-small-cell lung carcinoma: a proposal for quantitative immune-related pathologic response criteria (irPRC). Ann Oncol 29:1853-1860
Zhang, Jiajia; Quadri, Shafat; Wolfgang, Christopher L et al. (2018) New Development of Biomarkers for Gastrointestinal Cancers: From Neoplastic Cells to Tumor Microenvironment. Biomedicines 6:
Sun, Im-Hong; Oh, Min-Hee; Zhao, Liang et al. (2018) mTOR Complex 1 Signaling Regulates the Generation and Function of Central and Effector Foxp3+ Regulatory T Cells. J Immunol 201:481-492
Hyman, David M; Rizvi, Naiyer; Natale, Ronald et al. (2018) Phase I Study of MEDI3617, a Selective Angiopoietin-2 Inhibitor Alone and Combined with Carboplatin/Paclitaxel, Paclitaxel, or Bevacizumab for Advanced Solid Tumors. Clin Cancer Res 24:2749-2757
Guo, Hong; Barberi, Theresa; Suresh, Rahul et al. (2018) Progression from the Common Lymphoid Progenitor to B/Myeloid PreproB and ProB Precursors during B Lymphopoiesis Requires C/EBP?. J Immunol 201:1692-1704

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