Rutgers Cancer Institute of New Jersey (CINJ) is the State of New Jersey's only National Cancer Institute (NCI)-designated Comprehensive Cancer Center. The mission of CINJ is to reduce the burden of cancer by advancing cancer research, prevention, screening and education for one of the nation?s most diverse and densely populated states and therefore considers the entire State of New Jersey (NJ) its catchment area. With 21 counties, New Jersey is one of the most racially, ethnically and socioeconomically diverse regions in the US. The State is home to a large immigrant and minority population. As a whole, New Jersey is a well- educated and high-income state. However, this statistic conceals disparities in education level, English language proficiency, immigrant status, income, population density, and access to cancer care. The three major cities in the State - Newark, Trenton, and Camden - have a large population of minority, low income, and immigrant residents. The age-adjusted incidence rate of cancer in NJ is significantly higher than the US average. NJ ranked 6th in the nation in 2010-2014 in cancer incidence rates. The top five cancers in NJ mirror the top cancers in the US. Incidence of prostate, lung, colorectal, bladder, and melanoma ranked highest among men. Incidence of breast, lung, colorectal, uterine, and thyroid cancers ranked highest among women. The top five cancer sites with the highest mortality rates include lung, prostate, colorectal, and pancreas, liver for men and ovarian cancer for women. Cancer mortality in NJ is higher than the US average for colorectal cancer (men and women) and breast and pancreas cancers (women). Although overall cancer incidence in NJ has declined, there have been significant increases in breast, kidney (women), leukemia, liver, oral (men), pancreatic, and uterine cancers. Work conducted by CINJ investigators has elucidated a number of disparities in cancer incidence and mortality with regard to race/ethnicity and geographic location. This information has been used to guide research and outreach activities. CINJ conducts research and delivers outreach services that focus on cancers that pose a significant burden to the NJ population. Research and outreach services address barriers to access to cancer care and prevention services and modify health behaviors that are associated with increased cancer risk.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Center Core Grants (P30)
Project #
5P30CA072720-22
Application #
10112881
Study Section
Subcommittee I - Transistion to Independence (NCI)
Project Start
1997-03-01
Project End
2024-02-29
Budget Start
2021-03-01
Budget End
2022-02-28
Support Year
22
Fiscal Year
2021
Total Cost
Indirect Cost
Name
Rbhs -Cancer Institute of New Jersey
Department
Type
DUNS #
078728091
City
New Brunswick
State
NJ
Country
United States
Zip Code
08901
Perekatt, Ansu O; Shah, Pooja P; Cheung, Shannon et al. (2018) SMAD4 Suppresses WNT-Driven Dedifferentiation and Oncogenesis in the Differentiated Gut Epithelium. Cancer Res 78:4878-4890
Zhu, Sining; Jin, Juan; Gokhale, Samantha et al. (2018) Genetic Alterations of TRAF Proteins in Human Cancers. Front Immunol 9:2111
Hadigol, Mohammad; Khiabanian, Hossein (2018) MERIT reveals the impact of genomic context on sequencing error rate in ultra-deep applications. BMC Bioinformatics 19:219
Llanos, Adana A M; Tsui, Jennifer; Rotter, David et al. (2018) Factors associated with high-risk human papillomavirus test utilization and infection: a population-based study of uninsured and underinsured women. BMC Womens Health 18:162
Shih, Weichung Joe; Lin, Yong (2018) Relative efficiency of precision medicine designs for clinical trials with predictive biomarkers. Stat Med 37:687-709
Severson, Eric A; Riedlinger, Gregory M; Connelly, Caitlin F et al. (2018) Detection of clonal hematopoiesis of indeterminate potential in clinical sequencing of solid tumor specimens. Blood 131:2501-2505
Winer, Benjamin Y; Shirvani-Dastgerdi, Elham; Bram, Yaron et al. (2018) Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection. Sci Transl Med 10:
Ding, Qiang; Gaska, Jenna M; Douam, Florian et al. (2018) Species-specific disruption of STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease. Proc Natl Acad Sci U S A 115:E6310-E6318
Dai, Zhuqing; Feng, Simin; Liu, Anna et al. (2018) Anti-inflammatory effects of newly synthesized ?-galacto-oligosaccharides on dextran sulfate sodium-induced colitis in C57BL/6J mice. Food Res Int 109:350-357
Modi, Parth K; Wang, Ye; Kirk, Peter S et al. (2018) The Receipt of Industry Payments is Associated With Prescribing Promoted Alpha-blockers and Overactive Bladder Medications. Urology 117:50-56

Showing the most recent 10 out of 775 publications