Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HD013563-29
Application #
7028885
Study Section
Special Emphasis Panel (NSS)
Program Officer
Coulombe, James N
Project Start
1998-04-01
Project End
2008-03-31
Budget Start
2006-04-01
Budget End
2007-03-31
Support Year
29
Fiscal Year
2006
Total Cost
$453,951
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Hart, Gerald W; Slawson, Chad; Ramirez-Correa, Genaro et al. (2011) Cross talk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease. Annu Rev Biochem 80:825-58
Zachara, Natasha E; Molina, Henrik; Wong, Ker Yi et al. (2011) The dynamic stress-induced ""O-GlcNAc-ome"" highlights functions for O-GlcNAc in regulating DNA damage/repair and other cellular pathways. Amino Acids 40:793-808
Slawson, Chad; Hart, Gerald W (2011) O-GlcNAc signalling: implications for cancer cell biology. Nat Rev Cancer 11:678-84
Butkinaree, Chutikarn; Park, Kyoungsook; Hart, Gerald W (2010) O-linked beta-N-acetylglucosamine (O-GlcNAc): Extensive crosstalk with phosphorylation to regulate signaling and transcription in response to nutrients and stress. Biochim Biophys Acta 1800:96-106
Li, Xi; Molina, Henrik; Huang, Haiyan et al. (2009) O-linked N-acetylglucosamine modification on CCAAT enhancer-binding protein beta: role during adipocyte differentiation. J Biol Chem 284:19248-54
Housley, Michael P; Udeshi, Namrata D; Rodgers, Joseph T et al. (2009) A PGC-1alpha-O-GlcNAc transferase complex regulates FoxO transcription factor activity in response to glucose. J Biol Chem 284:5148-57
Zachara, Natasha E (2009) Detecting the ""O-GlcNAc-ome""; detection, purification, and analysis of O-GlcNAc modified proteins. Methods Mol Biol 534:251-79
Copeland, Ronald J; Bullen, John W; Hart, Gerald W (2008) Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity. Am J Physiol Endocrinol Metab 295:E17-28
Cheung, Win D; Hart, Gerald W (2008) AMP-activated protein kinase and p38 MAPK activate O-GlcNAcylation of neuronal proteins during glucose deprivation. J Biol Chem 283:13009-20
Slawson, Chad; Lakshmanan, T; Knapp, Spencer et al. (2008) A mitotic GlcNAcylation/phosphorylation signaling complex alters the posttranslational state of the cytoskeletal protein vimentin. Mol Biol Cell 19:4130-40

Showing the most recent 10 out of 76 publications