The Oregon Hearing Core (OHCC) Bioengineering Core (Core 1) will support six of the OHCC users and four collaborating investigators. The purpose of the Bioengineering core is to provide engineering and software expertise and to provide electrophysiological characterization of certain animals needed in projects of the users. In engineer will design and build custom electronic and mechanical devices that solve experimental and data acquisition problems. A computer programmer will write computer software (e.g. a Lab View virtual instrument) to address the experimental needs of the users. Projects undertaken by engineer and programmer will extend the funded work of the core users and stimulate collaborative studies between users. The programmer will help create common data bases that would allow sharing of experimental data among users. In addition, an electrophysiology technician will be available to measure (in mice, guinea pigs or gerbils) auditory brainstem responses, cochlear compound action potentials, distortion product otoacoustic emissions, and endocochlear potentials. An important activity of the technician will be to characterize the functional status of the cochlea in mutant mice produced by the OHCC Mouse Molecular Genetics Core. As for the engineer and programmer, the technician will work with Core users to extend work on supported R01s and enhance collaborative studies.
| Wang, Lingyan; Kempton, J Beth; Brigande, John V (2018) Gene Therapy in Mouse Models of Deafness and Balance Dysfunction. Front Mol Neurosci 11:300 |
| Oh, Yonghee; Reiss, Lina A J (2018) Binaural Pitch Fusion: Effects of Amplitude Modulation. Trends Hear 22:2331216518788972 |
| Kachelmeier, Allan; Shola, Tsering; Meier, William B et al. (2018) Simplified, automated methods for assessing pixel intensities of fluorescently-tagged drugs in cells. PLoS One 13:e0206628 |
| Krey, Jocelyn F; Dumont, Rachel A; Wilmarth, Philip A et al. (2018) ELMOD1 Stimulates ARF6-GTP Hydrolysis to Stabilize Apical Structures in Developing Vestibular Hair Cells. J Neurosci 38:843-857 |
| Reiss, Lina A J; Fowler, Jennifer R; Hartling, Curtis L et al. (2018) Binaural Pitch Fusion in Bilateral Cochlear Implant Users. Ear Hear 39:390-397 |
| Reiss, Lina A J; Shayman, Corey S; Walker, Emily P et al. (2017) Binaural pitch fusion: Comparison of normal-hearing and hearing-impaired listeners. J Acoust Soc Am 141:1909 |
| Erickson, Timothy; Morgan, Clive P; Olt, Jennifer et al. (2017) Integration of Tmc1/2 into the mechanotransduction complex in zebrafish hair cells is regulated by Transmembrane O-methyltransferase (Tomt). Elife 6: |
| Krey, J F; Wilmarth, P A; David, L L et al. (2017) Analysis of the Proteome of Hair-Cell Stereocilia by Mass Spectrometry. Methods Enzymol 585:329-354 |
| Adler, Henry J; Anbuhl, Kelsey L; Atcherson, Samuel R et al. (2017) Community network for deaf scientists. Science 356:386-387 |
| Oh, Yonghee; Reiss, Lina A J (2017) Binaural pitch fusion: Pitch averaging and dominance in hearing-impaired listeners with broad fusion. J Acoust Soc Am 142:780 |
Showing the most recent 10 out of 165 publications
