During the past several years, statistics from national samples of high school youth indicate alarming increases in rates of substance use. The primary aims of the proposed study are to: 1) experimentally compare the effectiveness of family-based treatment, Multidimensional Family Therapy (MDFT), with adolescent residential treatment, Adolescent Treatment Program (ATP), in ameliorating drug use and symptoms of co-morbidity among dually diagnosed adolescents; 2) identify the mechanisms by which each treatment achieves its effects; and 3) examine the cost effectiveness and cost off-set of each treatment. ATP is a multifaceted residential treatment based on a social learning approach. MDFT is a multidimensional and intensive, in-home family-based treatment that targets individual, familial, peer, and community influences on drug use. An experimental design is achieved by randomly assigning 200 dually diagnosed adolescents to 2 treatments (MDFT, ATP). Comprehensive assessments of outcome (drug abuse, conduct problems/delinquency, and psychosocial functioning) and change mechanisms (parenting, alliance, 12 step, and adolescent skills) are obtained at 6 time points (intake; 2, 4, 12, 18 months post-intake and termination). Measures of cost effectiveness and cost off-set are included as well as careful procedures for treatment integrity and its measurement. Analyses will include Hierarchical Linear Modeling, Structural Equation Modeling, Multiple Regression, and MANOVA, and utilize latent factor scores representing multiple perspectives on multiple traits.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Specialized Center (P50)
Project #
3P50DA011328-02S1
Application #
6104186
Study Section
Project Start
1999-03-01
Project End
2000-02-29
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
2
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Miami School of Medicine
Department
Type
DUNS #
City
Miami
State
FL
Country
United States
Zip Code
33146
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Liddle, H A; Rowe, C; Diamond, G M et al. (2000) Toward a developmental family therapy: the clinical utility of research on adolescence. J Marital Fam Ther 26:485-99
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Liddle, H A; Hogue, A (2000) A family-based, developmental-ecological preventive intervention for high-risk adolescents. J Marital Fam Ther 26:265-79

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