Project 1: Acoustic Plus Electric Hearing Preservation of residual acoustic hearing during cochlear implantation has become an important improvement in the performance of cochlear implants. Not only does it improve the performance of implants (particularly for noisy, real-world listening conditions) but also allows the treatment of patients with severe high-frequency hearing loss, who have substantial low-frequency hearing. This project proposes to continue this work on combining acoustic plus electric (A+E) hearing. In addition to the overall goal of improving patient care for hearing loss, several unique research opportunities arise from this work. The first opportunity arises because of the new population of patients that will be implanted with these A+E devices. Never before have patients with such high levels of pre-operative residual hearing been implanted in such a large- scale project. We are at the same time seeing levels of performance for the transmission of speech through the short electrode that are surprising in light of the previous literature. This will allow us to re-examine some of the commonly held beliefs about the limitations of electric stimulation due to channel interaction. The second opportunity arises because the short-electrode Hybrid implant assigns low- and mid-frequency speech bands to extreme basal locations in the cochlea. Thus we have a unique opportunity to study the effects of remapping, neural plasticity, and adaptation to highly-distorted place-frequency maps in the cochlea.

Public Health Relevance

This research has the potential to continue to influence clinical practice. The new populations of patients will be implanted with hearing preservation devices will allow us to potentially expand the performance ceilings for all cochlear implants. The knowledge we gain regarding adapting to these new hearing preservation electrodes will influence the designs of implants in the future as well.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Specialized Center (P50)
Project #
5P50DC000242-28
Application #
8606842
Study Section
Special Emphasis Panel (ZDC1)
Project Start
Project End
Budget Start
2014-02-01
Budget End
2015-01-31
Support Year
28
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Iowa
Department
Type
DUNS #
City
Iowa City
State
IA
Country
United States
Zip Code
Shearer, A Eliot; Tejani, Viral D; Brown, Carolyn J et al. (2018) In Vivo Electrocochleography in Hybrid Cochlear Implant Users Implicates TMPRSS3 in Spiral Ganglion Function. Sci Rep 8:14165
Adunka, Oliver F; Gantz, Bruce J; Dunn, Camille et al. (2018) Minimum Reporting Standards for Adult Cochlear Implantation. Otolaryngol Head Neck Surg 159:215-219
Smith, Nicholas A; McMurray, Bob (2018) Temporal Responsiveness in Mother-Child Dialogue: A Longitudinal Analysis of Children with Normal Hearing and Hearing Loss. Infancy 23:410-431
Wu, Yu-Hsiang; Stangl, Elizabeth; Chipara, Octav et al. (2018) Characteristics of Real-World Signal to Noise Ratios and Speech Listening Situations of Older Adults With Mild to Moderate Hearing Loss. Ear Hear 39:293-304
Gantz, Bruce J; Dunn, Camille C; Oleson, Jacob et al. (2018) Acoustic plus electric speech processing: Long-term results. Laryngoscope 128:473-481
Kim, Jeong-Seo; Tejani, Viral D; Abbas, Paul J et al. (2018) Postoperative Electrocochleography from Hybrid Cochlear Implant users: An Alternative Analysis Procedure. Hear Res 370:304-315
Goman, Adele M; Dunn, Camille C; Gantz, Bruce J et al. (2018) PREVALENCE OF POTENTIAL HYBRID AND CONVENTIONAL COCHLEAR IMPLANT CANDIDATES BASED ON AUDIOMETRIC PROFILE. Otol Neurotol 39:515-517
Bonnard, Damien; Schwalje, Adam; Gantz, Bruce et al. (2018) Electric and acoustic harmonic integration predicts speech-in-noise performance in hybrid cochlear implant users. Hear Res 367:223-230
Pimperton, Hannah; Walker, Elizabeth A (2018) Word Learning in Children With Cochlear Implants: Examining Performance Relative to Hearing Peers and Relations With Age at Implantation. Ear Hear 39:980-991
McMurray, Bob; Ellis, Tyler P; Apfelbaum, Keith S (2018) How Do You Deal With Uncertainty? Cochlear Implant Users Differ in the Dynamics of Lexical Processing of Noncanonical Inputs. Ear Hear :

Showing the most recent 10 out of 247 publications