The Human Translational Applications Core (P30-HTAC) supports the Consortium for NeuropsychiatricPhenomics (CNP) by providing services of three integrated units: (1) Human Recruitment and PhenotypingUnit; (2) Neuroimaging Unit; and (3) Statistics and Database Management Unit. The Human Recruitmentand Phenotyping Unit serves the CNP by recruiting all human subjects and conducting all diagnostic,behavioral, personality, and cognitive data needed by Components 3 and 4. The human samples include agroup of 2000 healthy people (referred to as the 'LA2K'), and 100 individuals in each of three diagnosticgroups (comprising people with the diagnoses of schizophrenia, bipolar disorder, and attentiondeficit/hyperactivity disorder), including people of both European and Hispanic/Latino ancestries. TheNeuroimaging Unit will be responsible for sthe conduct of structural and functional neuroimaging aspects(including structural magnetic resonance imaging, functional magnetic resonance imaging, and diffusiontensor imaging) required for Components 3 and 4, acquiring all relevant data and providing analysisexpertise to investigators within these components. The Statistics and Database Management Unit providesa range of statistical resource coordination, database management, and project management functions to allother CNP components. Each of the units within the P30-HTAC maintains standards to assure quality ofCNP data. Collectively the three units of the P30-HTAC provide high quality services to the CNP withefficiency difficult for any individual project to achieve. The P30-HTAC further integrates delivery of theseservices to sustain the synergy and interactions across components within the CNP. The P30-HTAC alsohas scientific aims beyond its service roles: its units actively seeks to develop new methods in humanbehavioral and cognitive assessment, neuroimaging, and statistical methods for optimal phenotype definitionand identification of relations between phenotypes and genotypes.
Showing the most recent 10 out of 39 publications
