Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Research Project (R01)
Project #
2R01AA009014-06A1
Application #
2045055
Study Section
Special Emphasis Panel (ZRG4-ALTX-3)
Project Start
1991-08-01
Project End
2001-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Colorado Denver
Department
Pharmacology
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045

  Publications

Bhave, Sanjiv V; Hoffman, Paula L (2004) Phosphatidylinositol 3'-OH kinase and protein kinase A pathways mediate the anti-apoptotic effect of pituitary adenylyl cyclase-activating polypeptide in cultured cerebellar granule neurons: modulation by ethanol. J Neurochem 88:359-69
Nelson, Eric J; Hellevuo, Kaisa; Yoshimura, Masami et al. (2003) Ethanol-induced phosphorylation and potentiation of the activity of type 7 adenylyl cyclase. Involvement of protein kinase C delta. J Biol Chem 278:4552-60
Kirstein, Shelli L; Davidson, Kirsten L; Ehringer, Marissa A et al. (2002) Quantitative trait loci affecting initial sensitivity and acute functional tolerance to ethanol-induced ataxia and brain cAMP signaling in BXD recombinant inbred mice. J Pharmacol Exp Ther 302:1238-45
Kirstein, S L; Tabakoff, B (2001) Genetic correlations between initial sensitivity to Ethanol and brain cAMP signaling in inbred and selectively bred mice. Alcohol Clin Exp Res 25:791-9
Tabakoff, B; Nelson, E; Yoshimura, M et al. (2001) Phosphorylation cascades control the actions of ethanol on cell cAMP signalling. J Biomed Sci 8:44-51
Wu, P H; Tabakoff, B; Szabo, G et al. (2001) Chronic ethanol exposure results in increased acute functional tolerance in selected lines of HAFT and LAFT mice. Psychopharmacology (Berl) 155:405-12
Yoshimura, M; Wu, P H; Hoffman, P L et al. (2000) Overexpression of type 7 adenylyl cyclase in the mouse brain enhances acute and chronic actions of morphine. Mol Pharmacol 58:1011-6
Bhave, S V; Snell, L D; Tabakoff, B et al. (1999) Ethanol sensitivity of NMDA receptor function in developing cerebellar granule neurons. Eur J Pharmacol 369:247-59
Yoshimura, M; Tabakoff, B (1999) Ethanol's actions on cAMP-mediated signaling in cells transfected with type VII adenylyl cyclase. Alcohol Clin Exp Res 23:1457-61
Rabbani, M; Nelson, E J; Hoffman, P L et al. (1999) Role of protein kinase C in ethanol-induced activation of adenylyl cyclase. Alcohol Clin Exp Res 23:77-86

Showing the most recent 10 out of 30 publications