|
Porcu, Patrizia; O'Buckley, Todd K; Song, Soomin C et al. (2011) Genetic analysis of the neurosteroid deoxycorticosterone and its relation to alcohol phenotypes: identification of QTLs and downstream gene regulation. PLoS One 6:e18405
|
|
Besheer, Joyce; Lindsay, Tessa G; O'Buckley, Todd K et al. (2010) Pregnenolone and ganaxolone reduce operant ethanol self-administration in alcohol-preferring p rats. Alcohol Clin Exp Res 34:2044-52
|
|
Porcu, Patrizia; O'Buckley, Todd K; Alward, Sarah E et al. (2010) Differential effects of ethanol on serum GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in mice, rats, cynomolgus monkeys, and humans. Alcohol Clin Exp Res 34:432-42
|
|
Ray, Lara A; Hutchison, Kent E; Ashenhurst, James R et al. (2010) Naltrexone selectively elevates GABAergic neuroactive steroid levels in heavy drinkers with the Asp40 allele of the OPRM1 gene: a pilot investigation. Alcohol Clin Exp Res 34:1479-87
|
|
Porcu, Patrizia; O'Buckley, Todd K; Alward, Sarah E et al. (2009) Simultaneous quantification of GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in human and rat serum. Steroids 74:463-73
|
|
Porcu, Patrizia; O'Buckley, Todd K; Leslie Morrow, A et al. (2008) Differential hypothalamic-pituitary-adrenal activation of the neuroactive steroids pregnenolone sulfate and deoxycorticosterone in healthy controls and alcohol-dependent subjects. Psychoneuroendocrinology 33:214-26
|
|
Marx, Christine E; VanDoren, Margaret J; Duncan, Gary E et al. (2003) Olanzapine and clozapine increase the GABAergic neuroactive steroid allopregnanolone in rodents. Neuropsychopharmacology 28:1-13
|
|
Marx, C E; Duncan, G E; Gilmore, J H et al. (2000) Olanzapine increases allopregnanolone in the rat cerebral cortex. Biol Psychiatry 47:1000-4
|
