Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
7R01AG007591-07
Application #
2049811
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1988-04-01
Project End
1995-04-30
Budget Start
1994-09-30
Budget End
1995-04-30
Support Year
7
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Trophix Pharmaceuticals, Inc.
Department
Type
DUNS #
City
South Plainfield
State
NJ
Country
United States
Zip Code
07080
Tang, X C; Kindel, G H; Kozikowski, A P et al. (1994) Comparison of the effects of natural and synthetic huperzine-A on rat brain cholinergic function in vitro and in vivo. J Ethnopharmacol 44:147-55
Hanin, I; Tang, X C; Kindel, G L et al. (1993) Natural and synthetic Huperzine A: effect on cholinergic function in vitro and in vivo. Ann N Y Acad Sci 695:304-6
Kozikowski, A P; Miller, C P; Yamada, F et al. (1991) Delineating the pharmacophoric elements of huperzine A: importance of the unsaturated three-carbon bridge to its AChE inhibitory activity. J Med Chem 34:3399-402
McKinney, M; Miller, J H; Yamada, F et al. (1991) Potencies and stereoselectivities of enantiomers of huperzine A for inhibition of rat cortical acetylcholinesterase. Eur J Pharmacol 203:303-5