Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG008076-06
Application #
2050026
Study Section
Neurology A Study Section (NEUA)
Project Start
1991-02-01
Project End
2000-01-31
Budget Start
1996-03-05
Budget End
1997-01-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Institute for Basic Research in Dev Disabil
Department
Type
DUNS #
167205090
City
Staten Island
State
NY
Country
United States
Zip Code
10314
Hua, Q; He, R Q; Haque, N et al. (2003) Microtubule associated protein tau binds to double-stranded but not single-stranded DNA. Cell Mol Life Sci 60:413-21
An, Wen-Lin; Cowburn, Richard F; Li, Lin et al. (2003) Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease. Am J Pathol 163:591-607
Tatebayashi, Yoshitaka; Lee, Moon H; Li, Liang et al. (2003) The dentate gyrus neurogenesis: a therapeutic target for Alzheimer's disease. Acta Neuropathol (Berl) 105:225-32
Liu, F; Zaidi, T; Iqbal, K et al. (2002) Aberrant glycosylation modulates phosphorylation of tau by protein kinase A and dephosphorylation of tau by protein phosphatase 2A and 5. Neuroscience 115:829-37
Iqbal, Khalid; Grundke-Iqbal, Inge (2002) Neurofibrillary pathology leads to synaptic loss and not the other way around in Alzheimer disease. J Alzheimers Dis 4:235-8
Pei, Jin-Jing; Braak, Heiko; Gong, Cheng-Xin et al. (2002) Up-regulation of cell division cycle (cdc) 2 kinase in neurons with early stage Alzheimer's disease neurofibrillary degeneration. Acta Neuropathol (Berl) 104:369-76
Pei, Jin-Jing; Braak, Heiko; An, Wen-Lin et al. (2002) Up-regulation of mitogen-activated protein kinases ERK1/2 and MEK1/2 is associated with the progression of neurofibrillary degeneration in Alzheimer's disease. Brain Res Mol Brain Res 109:45-55
Hu, Yuan Yuan; He, Shan Shu; Wang, Xiaochuan et al. (2002) Levels of nonphosphorylated and phosphorylated tau in cerebrospinal fluid of Alzheimer's disease patients : an ultrasensitive bienzyme-substrate-recycle enzyme-linked immunosorbent assay. Am J Pathol 160:1269-78
Liu, Fei; Zaidi, Tanweer; Iqbal, Khalid et al. (2002) Role of glycosylation in hyperphosphorylation of tau in Alzheimer's disease. FEBS Lett 512:101-6
Iqbal, K; Alonso, A del C; El-Akkad, E et al. (2002) Pharmacological targets to inhibit Alzheimer neurofibrillary degeneration. J Neural Transm Suppl :309-19

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