Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
3R01AG008278-08S1
Application #
3119840
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1988-08-01
Project End
1993-07-31
Budget Start
1990-03-01
Budget End
1990-07-31
Support Year
8
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Mc Lean Hospital (Belmont, MA)
Department
Type
DUNS #
City
Belmont
State
MA
Country
United States
Zip Code
02478
Nusblat, Leora M; Carroll, Molly J; Roth, Charles M (2017) Crosstalk between M2 macrophages and glioma stem cells. Cell Oncol (Dordr) 40:471-482
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Mohan, P S; Nixon, R A (1995) Purification and properties of high molecular weight calpastatin from bovine brain. J Neurochem 64:859-66
Cataldo, A M; Barnett, J L; Berman, S A et al. (1995) Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: evidence for early up-regulation of the endosomal-lysosomal system. Neuron 14:671-80
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Nixon, R A (1994) Neuronal degenerative mechanisms as clues to pathogenesis and treatment of Alzheimer's disease. Neurobiol Aging 15 Suppl 2:S61-5
Cataldo, A M; Hamilton, D J; Nixon, R A (1994) Lysosomal abnormalities in degenerating neurons link neuronal compromise to senile plaque development in Alzheimer disease. Brain Res 640:68-80
Burke, W J; Galvin, N J; Chung, H D et al. (1994) Degenerative changes in epinephrine tonic vasomotor neurons in Alzheimer's disease. Brain Res 661:35-42
Saito, K; Elce, J S; Hamos, J E et al. (1993) Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration. Proc Natl Acad Sci U S A 90:2628-32
Saito, K; Nixon, R A (1993) Specificity of calcium-activated neutral proteinase (CANP) inhibitors for human mu CANP and mCANP. Neurochem Res 18:231-3

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