When faced with a difficult problem, people often rely on their past experiences. Healthy aging impairs both episodic memory and everyday problem solving. Dr. Nadia Brashier, a postdoctoral fellow in the Psychology Department at Harvard University, and her mentor, Dr. Daniel Schacter, will use the Research Supplement to Promote Diversity in Health-Related Research (PA-20-222) to investigate whether altered connectivity between large-scale brain networks underlies older adults? deficits. This supplement will enhance the training of Dr. Brashier, an early career scientist from a disadvantaged background. She will develop expertise in the cognitive neuroscience of aging, with a focus on using functional magnetic resonance imaging (fMRI) methods in older adults.

Public Health Relevance

Episodic memory declines with age, with negative consequences for everyday problem solving. This research is the first to identify what neural changes prevent older adults from drawing on past solutions to solve current problems. Dysregulation in connectivity between large-scale brain networks may constrain older adults, with implications for their ability to live independently.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
3R01AG008441-28S1
Application #
10218343
Study Section
Program Officer
Wagster, Molly V
Project Start
1989-08-04
Project End
2022-11-30
Budget Start
2020-09-15
Budget End
2020-11-30
Support Year
28
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Harvard University
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
082359691
City
Cambridge
State
MA
Country
United States
Zip Code
02138
Seli, Paul; Kane, Michael J; Smallwood, Jonathan et al. (2018) Mind-Wandering as a Natural Kind: A Family-Resemblances View. Trends Cogn Sci 22:479-490
Carpenter, Alexis C; Schacter, Daniel L (2018) False memories, false preferences: Flexible retrieval mechanisms supporting successful inference bias novel decisions. J Exp Psychol Gen 147:988-1004
Cao, Xiancai; Madore, Kevin P; Wang, Dahua et al. (2018) Remembering the past and imagining the future: attachment effects on production of episodic details in close relationships. Memory 26:1140-1150
Madore, Kevin P; Jing, Helen G; Schacter, Daniel L (2018) Selective effects of specificity inductions on episodic details: evidence for an event construction account. Memory :1-11
Schacter, Daniel L (2018) Implicit Memory, Constructive Memory, and Imagining the Future: A Career Perspective. Perspect Psychol Sci :1745691618803640
Carpenter, Alexis C; Schacter, Daniel L (2018) Flexible retrieval mechanisms supporting successful inference produce false memories in younger but not older adults. Psychol Aging 33:134-143
Devitt, Aleea L; Schacter, Daniel L (2018) An Optimistic Outlook Creates a Rosy Past: The Impact of Episodic Simulation on Subsequent Memory. Psychol Sci 29:936-946
Thakral, Preston P; Madore, Kevin P; Schacter, Daniel L (2018) Content-specific phenomenological similarity between episodic memory and simulation. Memory :1-6
De Brigard, Felipe; Hanna, Eleanor; St Jacques, Peggy L et al. (2018) How thinking about what could have been affects how we feel about what was. Cogn Emot :1-14
Seli, Paul; Smilek, Daniel; Ralph, Brandon C W et al. (2018) The awakening of the attention: Evidence for a link between the monitoring of mind wandering and prospective goals. J Exp Psychol Gen 147:431-443

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