Funds are requested to conduct two in-person follow-ups of the Hispanic EPESE (Established Populations for Epidemiologic Studies of the Elderly) giving us a total of four contacts (1993-4, 1995-6, 1998-9, and 2000-2001). The study's original aims were to provide basic data on the health and health care needs of Mexican American elderly in the Southwestern United States. The baseline cohort of 3,050 subjects was followed up two years later. Additional follow-ups are requested at five and seven years to enable the assessment of changes in health and well-being over time. Key health outcomes include mortality, physical functioning, and depression. Of particular interest is how the latter three outcomes are interrelated in predicting each other over time as well as predicting mortality over time. In addition to investigating trajectories of change, we examine how medical conditions, such as diabetes, obesity and arthritis, and social factors, such as migration status, social support and acculturation are associated with changes in health outcomes over time. Our two-year follow-up data indicate that very few elderly Mexican Americans enter nursing homes despite having high rates of physical disability, cognitive dysfunction, and depression. Thus, many disabled elderly Mexican Americans are cared for in the home. In addition to investigating circumstances under which some Mexican Americans become institutionalized over time, we plan to assess the role of the family in caring for disabled elderly members in the home. The third and fourth waves of data collection requested will repeat interview measures on key health outcomes and predictor variables as well as in-home medical assessments that include blood pressures, measures of height and weight, and performance measures of physical functioning. A variety of statistical procedures are planned for analyzing trajectories of change in health outcomes and how these changes are associated with medical conditions and social factors over time. The longitudinal research proposed will provide essential information necessary for addressing the health care needs of older Mexican Americans.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Research Project (R01)
Project #
Application #
Study Section
Epidemiology and Disease Control Subcommittee 2 (EDC)
Program Officer
Stahl, Sidney M
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Texas Medical Br Galveston
Public Health & Prev Medicine
Schools of Medicine
United States
Zip Code
Howrey, Bret T; Al Snih, Soham; Markides, Kyriakos S et al. (2018) Frailty and diabetes among Mexican American older adults. Ann Epidemiol 28:421-426.e1
Mutambudzi, Miriam; Chen, Nai-Wei; Howrey, Bret et al. (2018) Physical Performance Trajectories and Mortality among Older Mexican Americans. J Gerontol A Biol Sci Med Sci :
Garcia, Marc A; Reyes, Adriana M (2018) Physical Functioning and Disability Trajectories by Age of Migration Among Mexican Elders in the United States. J Gerontol B Psychol Sci Soc Sci 73:1292-1302
Garcia, Marc A; Reyes, Adriana M (2018) Physical Functioning and Disability Trajectories by Age of Migration Among Mexican Elders in the United States. J Gerontol B Psychol Sci Soc Sci :
Lewis, Zakkoyya H; Markides, Kyriakos S; Ottenbacher, Kenneth J et al. (2018) The Impact of 10-Year Physical Activity Changes on 7-Year Mortality in Older Mexican Americans. J Phys Act Health 15:30-39
Li, Chih-Ying; Al Snih, Soham; Karmarkar, Amol et al. (2018) Early frailty transition predicts 15-year mortality among nondisabled older Mexican Americans. Ann Epidemiol 28:362-367.e3
Garcia, Marc A; Reyes, Adriana M (2018) Prevalence and Trends in Morbidity and Disability Among Older Mexican Americans in the Southwestern United States, 1993-2013. Res Aging 40:311-339
Garcia, Marc A; Saenz, Joseph L; Downer, Brian et al. (2018) Age of Migration Differentials in Life Expectancy With Cognitive Impairment: 20-Year Findings From the Hispanic-EPESE. Gerontologist 58:894-903
Downer, Brian; Garcia, Marc A; Saenz, Joseph et al. (2018) The Role of Education in the Relationship Between Age of Migration to the United States and Risk of Cognitive Impairment Among Older Mexican Americans. Res Aging 40:411-431
Downer, Brian; Al Snih, Soham; Howrey, Bret T et al. (2018) Combined effects of cognitive impairment and pre-frailty on future frailty and death in older Mexican Americans. Aging Ment Health :1-8

Showing the most recent 10 out of 215 publications