|
Refolo, L M; Pappolla, M A; LaFrancois, J et al. (2001) A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease. Neurobiol Dis 8:890-9
|
|
Refolo, L M; Malester, B; LaFrancois, J et al. (2000) Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model. Neurobiol Dis 7:321-31
|
|
Poeggeler, B; Pappolla, M A; Hardeland, R et al. (1999) Indole-3-propionate: a potent hydroxyl radical scavenger in rat brain. Brain Res 815:382-8
|
|
Chyan, Y J; Poeggeler, B; Omar, R A et al. (1999) Potent neuroprotective properties against the Alzheimer beta-amyloid by an endogenous melatonin-related indole structure, indole-3-propionic acid. J Biol Chem 274:21937-42
|
|
Pappolla, M A; Chyan, Y J; Omar, R A et al. (1998) Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo. Am J Pathol 152:871-7
|
|
Pappolla, M; Bozner, P; Soto, C et al. (1998) Inhibition of Alzheimer beta-fibrillogenesis by melatonin. J Biol Chem 273:7185-8
|
|
Bozner, P; Grishko, V; LeDoux, S P et al. (1997) The amyloid beta protein induces oxidative damage of mitochondrial DNA. J Neuropathol Exp Neurol 56:1356-62
|
|
Pappolla, M A; Sos, M; Omar, R A et al. (1997) Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide. J Neurosci 17:1683-90
|
