Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
5R01AG012527-02
Application #
2054167
Study Section
Special Emphasis Panel (ZRG1-BPO (02))
Project Start
1995-05-15
Project End
2000-04-30
Budget Start
1996-05-29
Budget End
1997-04-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Surgery
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Uryu, Kunihiro; Chen, Xiao-Han; Martinez, Dan et al. (2007) Multiple proteins implicated in neurodegenerative diseases accumulate in axons after brain trauma in humans. Exp Neurol 208:185-92
Maxwell, William L; MacKinnon, Mary Anne; Smith, Douglas H et al. (2006) Thalamic nuclei after human blunt head injury. J Neuropathol Exp Neurol 65:478-88
Stein, Sherman C; Graham, David I; Chen, Xiao-Han et al. (2005) Apo E genotype not associated with intravascular coagulation in traumatic brain injury. Neurosci Lett 387:28-31
Stein, Sherman C; Graham, David I; Chen, Xiao-Han et al. (2004) Association between intravascular microthrombosis and cerebral ischemia in traumatic brain injury. Neurosurgery 54:687-91; discussion 691
Maxwell, W L; Dhillon, K; Harper, L et al. (2003) There is differential loss of pyramidal cells from the human hippocampus with survival after blunt head injury. J Neuropathol Exp Neurol 62:272-9
Smith, Douglas H; Meaney, David F; Shull, William H (2003) Diffuse axonal injury in head trauma. J Head Trauma Rehabil 18:307-16
Smith, Douglas H; Uryu, Kunihiro; Saatman, Kathryn E et al. (2003) Protein accumulation in traumatic brain injury. Neuromolecular Med 4:59-72
Wolf, J A; Stys, P K; Lusardi, T et al. (2001) Traumatic axonal injury induces calcium influx modulated by tetrodotoxin-sensitive sodium channels. J Neurosci 21:1923-30
Smith, D H; Wolf, J A; Meaney, D F (2001) A new strategy to produce sustained growth of central nervous system axons: continuous mechanical tension. Tissue Eng 7:131-9
Leoni, M J; Chen, X H; Mueller, A L et al. (2000) NPS 1506 attenuates cognitive dysfunction and hippocampal neuron death following brain trauma in the rat. Exp Neurol 166:442-9

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