Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Project (R01)
Project #
7R01AG014121-02
Application #
2457595
Study Section
Cardiovascular and Pulmonary Research A Study Section (CVA)
Project Start
1996-09-30
Project End
2002-07-31
Budget Start
1997-08-01
Budget End
1998-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Allegheny University of Health Sciences
Department
Type
Other Domestic Higher Education
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19129

  Publications

Vatner, Dorothy E; Yan, Lin; Lai, Lo et al. (2015) Type 5 adenylyl cyclase disruption leads to enhanced exercise performance. Aging Cell 14:1075-84
Iwatsubo, Kosaku; Bravo, Claudio; Uechi, Masami et al. (2012) Prevention of heart failure in mice by an antiviral agent that inhibits type 5 cardiac adenylyl cyclase. Am J Physiol Heart Circ Physiol 302:H2622-8
Guellich, Aziz; Gao, Shumin; Hong, Chull et al. (2010) Effects of cardiac overexpression of type 6 adenylyl cyclase affects on the response to chronic pressure overload. Am J Physiol Heart Circ Physiol 299:H707-12
Depre, Christophe; Park, Ji Yeon; Shen, You-Tang et al. (2010) Molecular mechanisms mediating preconditioning following chronic ischemia differ from those in classical second window. Am J Physiol Heart Circ Physiol 299:H752-62
Ho, David; Yan, Lin; Iwatsubo, Kousaku et al. (2010) Modulation of beta-adrenergic receptor signaling in heart failure and longevity: targeting adenylyl cyclase type 5. Heart Fail Rev 15:495-512
Shen, Weiqun; Vatner, Dorothy E; Vatner, Stephen F et al. (2010) Progressive loss of creatine maintains a near normal DeltaG approximately (ATP) in transgenic mouse hearts with cardiomyopathy caused by overexpressing Gsalpha. J Mol Cell Cardiol 48:591-9
Vatner, Stephen F; Yan, Lin; Ishikawa, Yoshihiro et al. (2009) Adenylyl cyclase type 5 disruption prolongs longevity and protects the heart against stress. Circ J 73:195-200
Hu, Che-Lin; Chandra, Rachna; Ge, Hui et al. (2009) Adenylyl cyclase type 5 protein expression during cardiac development and stress. Am J Physiol Heart Circ Physiol 297:H1776-82
Wu, Changgong; Yan, Lin; Depre, Christophe et al. (2009) Cytochrome c oxidase III as a mechanism for apoptosis in heart failure following myocardial infarction. Am J Physiol Cell Physiol 297:C928-34
Park, Misun; Shen, You-Tang; Gaussin, Vinciane et al. (2009) Apoptosis predominates in nonmyocytes in heart failure. Am J Physiol Heart Circ Physiol 297:H785-91

Showing the most recent 10 out of 71 publications