Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI015607-17
Application #
2060246
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1979-01-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Alabama Birmingham
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294

  Publications

Szalai, A J; Agrawal, A; Greenhough, T J et al. (1999) C-reactive protein: structural biology and host defense function. Clin Chem Lab Med 37:265-70
Szalai, A J; van Ginkel, F W; Dalrymple, S A et al. (1998) Testosterone and IL-6 requirements for human C-reactive protein gene expression in transgenic mice. J Immunol 160:5294-9
Agrawal, A; Lee, S; Carson, M et al. (1997) Site-directed mutagenesis of the phosphocholine-binding site of human C-reactive protein: role of Thr76 and Trp67. J Immunol 158:345-50
Szalai, A J; Briles, D E; Volanakis, J E (1996) Role of complement in C-reactive-protein-mediated protection of mice from Streptococcus pneumoniae. Infect Immun 64:4850-3
Szalai, A J; Briles, D E; Volanakis, J E (1995) Human C-reactive protein is protective against fatal Streptococcus pneumoniae infection in transgenic mice. J Immunol 155:2557-63
Agrawal, A; Volanakis, J E (1994) Probing the C1q-binding site on human C-reactive protein by site-directed mutagenesis. J Immunol 152:5404-10
Agrawal, A; Xu, Y; Ansardi, D et al. (1992) Probing the phosphocholine-binding site of human C-reactive protein by site-directed mutagenesis. J Biol Chem 267:25353-8
Kilpatrick, J M; Gresham, H D; Griffin Jr, F M et al. (1987) Peripheral blood mononuclear leukocytes release a mediator(s) that induces phagocytosis of C-reactive protein-coated cells by polymorphonuclear leukocytes. J Leukoc Biol 41:150-5
Horowitz, J; Volanakis, J E; Briles, D E (1987) Blood clearance of Streptococcus pneumoniae by C-reactive protein. J Immunol 138:2598-603
Gresham, H D; Clement, L T; Volanakis, J E et al. (1987) Cholera toxin and pertussis toxin regulate the Fc receptor-mediated phagocytic response of human neutrophils in a manner analogous to regulation by monoclonal antibody 1C2. J Immunol 139:4159-66

Showing the most recent 10 out of 13 publications