Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI031155-05
Application #
2066169
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1991-04-01
Project End
1997-03-31
Budget Start
1995-04-01
Budget End
1997-03-31
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
Klarskov, Klaus; Johnson, Kenneth L; Benson, Linda M et al. (2003) Structural characterization of a case-implicated contaminant, ""Peak X,"" in commercial preparations of 5-hydroxytryptophan. J Rheumatol 30:89-95
Naylor, S; Williamson, B L; Johnson, K L et al. (1999) Structural characterization of case-associated contaminants peak C and FF in L-tryptophan implicated in eosinophilia-myalgia syndrome. Adv Exp Med Biol 467:453-60
Kubo, H; Loegering, D A; Tohda, Y et al. (1999) Discordant and anomalous results among cytotoxicity assays: the confounding properties of eosinophil granule major basic protein on cell viability assays. J Immunol Methods 227:1-15
Kubo, H; Loegering, D A; Adolphson, C R et al. (1999) Cytotoxic properties of eosinophil granule major basic protein for tumor cells. Int Arch Allergy Immunol 118:426-8
Johnson, K L; Klarskov, K; Benson, L M et al. (1999) Presence of peak X and related compounds: the reported contaminant in case related 5-hydroxy-L-tryptophan associated with eosinophilia-myalgia syndrome. J Rheumatol 26:2714-7
Klarskov, K; Johnson, K L; Benson, L M et al. (1999) Eosinophilia-myalgia syndrome case-associated contaminants in commercially available 5-hydroxytryptophan. Adv Exp Med Biol 467:461-8
Naylor, S; Johnson, K L; Williamson, B L et al. (1999) Structural characterization of contaminants in commercial preparations of melatonin by on-line HPLC-electrospray ionization-tandem mass spectrometry. Adv Exp Med Biol 467:769-77
Williamson, B L; Johnson, K L; Tomlinson, A J et al. (1998) On-line HPLC-tandem mass spectrometry structural characterization of case-associated contaminants of L-tryptophan implicated with the onset of eosinophilia myalgia syndrome. Toxicol Lett 99:139-50
Williamson, B L; Tomlinson, A J; Mishra, P K et al. (1998) Structural characterization of contaminants found in commercial preparations of melatonin: similarities to case-related compounds from L-tryptophan associated with eosinophilia-myalgia syndrome. Chem Res Toxicol 11:234-40
Williamson, B L; Tomlinson, A J; Hurth, K M et al. (1998) Rapid HPLC screening method for contaminants found in implicated L-tryptophan associated with eosinophilia myalgia syndrome and adulterated rapeseed oil associated with toxic oil syndrome. Biomed Chromatogr 12:255-61

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