Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI034721-03
Application #
2069861
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1994-05-01
Project End
1998-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Virginia
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Olivieri, Kevin C; Scoggins, Robert M; Broderick, Brooks et al. (2008) Nef does not contribute to replication differences between R5 pre-AIDS and AIDS HIV-1 clones from patient ACH142. Retrovirology 5:42
Olivieri, Kevin; Scoggins, Robert M; Bor, Yeou-cherng et al. (2007) The envelope gene is a cytopathic determinant of CCR5 tropic HIV-1. Virology 358:23-38
Swartz, Jennifer E; Bor, Yeou-Cherng; Misawa, Yukiko et al. (2007) The shuttling SR protein 9G8 plays a role in translation of unspliced mRNA containing a constitutive transport element. J Biol Chem 282:19844-53
Levesque, Lyne; Bor, Yeou-Cherng; Matzat, Leah H et al. (2006) Mutations in tap uncouple RNA export activity from translocation through the nuclear pore complex. Mol Biol Cell 17:931-43
Forrest, Scott T; Barringhaus, Kurt G; Perlegas, Demetra et al. (2004) Intron retention generates a novel Id3 isoform that inhibits vascular lesion formation. J Biol Chem 279:32897-903
Alexander, Melissa; Bor, Yeou-cherng; Ravichandran, Kodimangalam S et al. (2004) Human immunodeficiency virus type 1 Nef associates with lipid rafts to downmodulate cell surface CD4 and class I major histocompatibility complex expression and to increase viral infectivity. J Virol 78:1685-96
Coyle, John H; Guzik, Brian W; Bor, Yeou-Cherng et al. (2003) Sam68 enhances the cytoplasmic utilization of intron-containing RNA and is functionally regulated by the nuclear kinase Sik/BRK. Mol Cell Biol 23:92-103
Jin, Li; Guzik, Brian W; Bor, Yeou-cherng et al. (2003) Tap and NXT promote translation of unspliced mRNA. Genes Dev 17:3075-86
Levesque, L; Guzik, B; Guan, T et al. (2001) RNA export mediated by tap involves NXT1-dependent interactions with the nuclear pore complex. J Biol Chem 276:44953-62
Guzik, B W; Levesque, L; Prasad, S et al. (2001) NXT1 (p15) is a crucial cellular cofactor in TAP-dependent export of intron-containing RNA in mammalian cells. Mol Cell Biol 21:2545-54

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