Immunogenicity of HIV Proteins Delivered by Live Vector

Paterson, Yvonne J.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 2R01AI036657-05
• Application #: 6020249
• Study Section: Special Emphasis Panel (ZRG1-AARR-2 (01))
• Program Officer: Bradac, James A
• Project Start: 1995-09-01
• Project End: 2003-08-31
• Budget Start: 1999-09-15
• Budget End: 2000-08-31
• Support Year: 5
• Fiscal Year: 1999

Institution

• Name: University of Pennsylvania
• Department: Microbiology/Immun/Virology
• Type: Schools of Medicine
• DUNS #: 042250712
• City: Philadelphia
• State: PA
• Country: United States
• Zip Code: 19104

Publications

Grenfell, Rafaella F Q; Shollenberger, Lisa M; Samli, E Farah et al. (2015) Vaccine self-assembling immune matrix is a new delivery platform that enhances immune responses to recombinant HBsAg in mice. Clin Vaccine Immunol 22:336-43

Neeson, Paul; Boyer, Jean; Kumar, Sanjeev et al. (2006) A DNA prime-oral Listeria boost vaccine in rhesus macaques induces a SIV-specific CD8 T cell mucosal response characterized by high levels of alpha4beta7 integrin and an effector memory phenotype. Virology 354:299-315

Boyer, Jean D; Maciag, Paulo C; Parkinson, Rose et al. (2006) Rhesus macaques with high levels of vaccine induced IFN-gamma producing cells better control viral set-point following challenge with SIV239. Vaccine 24:4498-502

Boyer, Jean D; Robinson, Tara M; Maciag, Paulo C et al. (2005) DNA prime Listeria boost induces a cellular immune response to SIV antigens in the rhesus macaque model that is capable of limited suppression of SIV239 viral replication. Virology 333:88-101

Peters, Christian; Peng, Xiaohui; Douven, Dennis et al. (2003) The induction of HIV Gag-specific CD8+ T cells in the spleen and gut-associated lymphoid tissue by parenteral or mucosal immunization with recombinant Listeria monocytogenes HIV Gag. J Immunol 170:5176-87