Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI037241-09
Application #
6761764
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Program Officer
Baker, Phillip J
Project Start
1994-09-30
Project End
2006-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
9
Fiscal Year
2004
Total Cost
$402,500
Indirect Cost

  Institution

Name
Boston Medical Center
Department
Type
DUNS #
005492160
City
Boston
State
MA
Country
United States
Zip Code
02118

  Publications

Zhao, Zhihui; Fleming, Rhonda; McCloud, Bilaal et al. (2007) CD14 mediates cross talk between mononuclear cells and fibroblasts for upregulation of matrix metalloproteinase 9 by Borrelia burgdorferi. Infect Immun 75:3062-9
Zhao, Zhihui; McCloud, Bilaal; Fleming, Rhonda et al. (2007) Borrelia burgdorferi-induced monocyte chemoattractant protein-1 production in vivo and in vitro. Biochem Biophys Res Commun 358:528-33
Wang, Xing-Guo; Kidder, J Michael; Scagliotti, Joanna P et al. (2004) Analysis of differences in the functional properties of the substrate binding proteins of the Borrelia burgdorferi oligopeptide permease (Opp) operon. J Bacteriol 186:51-60
Fleming, R V; Marques, A R; Klempner, M S et al. (2004) Pre-treatment and post-treatment assessment of the C(6) test in patients with persistent symptoms and a history of Lyme borreliosis. Eur J Clin Microbiol Infect Dis 23:615-8
Zhao, Zhihui; Chang, Hernan; Trevino, Richard P et al. (2003) Selective up-regulation of matrix metalloproteinase-9 expression in human erythema migrans skin lesions of acute lyme disease. J Infect Dis 188:1098-104
Lin, B; Kidder, J M; Noring, R et al. (2001) Differences in synovial fluid levels of matrix metalloproteinases suggest separate mechanisms of pathogenesis in Lyme arthritis before and after antibiotic treatment. J Infect Dis 184:174-80
Lin, B; Short, S A; Eskildsen, M et al. (2001) Functional testing of putative oligopeptide permease (Opp) proteins of Borrelia burgdorferi: a complementation model in opp(-) Escherichia coli. Biochim Biophys Acta 1499:222-31
Perides, G; Tanner-Brown, L M; Eskildsen, M A et al. (1999) Borrelia burgdorferi induces matrix metalloproteinases by neural cultures. J Neurosci Res 58:779-90
Perides, G; Charness, M E; Tanner, L M et al. (1998) Matrix metalloproteinases in the cerebrospinal fluid of patients with Lyme neuroborreliosis. J Infect Dis 177:401-8
Hu, L T; Klempner, M S (1997) Host-pathogen interactions in the immunopathogenesis of Lyme disease. J Clin Immunol 17:354-65

Showing the most recent 10 out of 15 publications