Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI045580-06
Application #
6760998
Study Section
Special Emphasis Panel (ZRG1-BM-1 (01))
Program Officer
Perdue, Samuel S
Project Start
1999-07-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
6
Fiscal Year
2004
Total Cost
$268,888
Indirect Cost
Name
University of Florida
Department
Pathology
Type
Schools of Veterinary Medicine
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Granquist, Erik G; Stuen, Snorre; Crosby, Liliana et al. (2010) Variant-specific and diminishing immune responses towards the highly variable MSP2(P44) outer membrane protein of Anaplasma phagocytophilum during persistent infection in lambs. Vet Immunol Immunopathol 133:117-24
Wamsley, Heather L; Barbet, Anthony F (2008) In situ detection of Anaplasma spp. by DNA target-primed rolling-circle amplification of a padlock probe and intracellular colocalization with immunofluorescently labeled host cell von Willebrand factor. J Clin Microbiol 46:2314-9
Granquist, Erik G; Stuen, Snorre; Lundgren, Anna M et al. (2008) Outer membrane protein sequence variation in lambs experimentally infected with Anaplasma phagocytophilum. Infect Immun 76:120-6
Palmer, Guy H; Futse, James E; Knowles Jr, Donald P et al. (2006) Insights into mechanisms of bacterial antigenic variation derived from the complete genome sequence of Anaplasma marginale. Ann N Y Acad Sci 1078:15-25
Barbet, Anthony F; Lundgren, Anna M; Alleman, A Rick et al. (2006) Structure of the expression site reveals global diversity in MSP2 (P44) variants in Anaplasma phagocytophilum. Infect Immun 74:6429-37
Noh, Susan M; Brayton, Kelly A; Knowles, Donald P et al. (2006) Differential expression and sequence conservation of the Anaplasma marginale msp2 gene superfamily outer membrane proteins. Infect Immun 74:3471-9
Brayton, Kelly A; Kappmeyer, Lowell S; Herndon, David R et al. (2005) Complete genome sequencing of Anaplasma marginale reveals that the surface is skewed to two superfamilies of outer membrane proteins. Proc Natl Acad Sci U S A 102:844-9
Rodriguez, Jose-Luis; Palmer, Guy H; Knowles Jr, Donald P et al. (2005) Distinctly different msp2 pseudogene repertoires in Anaplasma marginale strains that are capable of superinfection. Gene 361:127-32
Zika, Eleni; Fauquier, Lucas; Vandel, Laurence et al. (2005) Interplay among coactivator-associated arginine methyltransferase 1, CBP, and CIITA in IFN-gamma-inducible MHC-II gene expression. Proc Natl Acad Sci U S A 102:16321-6
Brown, Wendy C; Palmer, Guy H; Brayton, Kelly A et al. (2004) CD4+ T lymphocytes from Anaplasma marginale major surface protein 2 (MSP2) vaccinees recognize naturally processed epitopes conserved in MSP3. Infect Immun 72:3688-92

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