Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI050606-02
Application #
6683606
Study Section
Allergy and Immunology Study Section (ALY)
Program Officer
Mallia, Conrad M
Project Start
2002-12-01
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$262,120
Indirect Cost
Name
University of California Irvine
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
046705849
City
Irvine
State
CA
Country
United States
Zip Code
92697
Walsh, Craig M; Edinger, Aimee L (2010) The complex interplay between autophagy, apoptosis, and necrotic signals promotes T-cell homeostasis. Immunol Rev 236:95-109
Walsh, Craig M; Bell, Bryan D (2010) T cell intrinsic roles of autophagy in promoting adaptive immunity. Curr Opin Immunol 22:321-5
Hernandez, Jeniffer B; Newton, Ryan H; Walsh, Craig M (2010) Life and death in the thymus--cell death signaling during T cell development. Curr Opin Cell Biol 22:865-71
Arechiga, Adrian F; Bell, Bryan D; Leverrier, Sabrina et al. (2007) A Fas-associated death domain protein/caspase-8-signaling axis promotes S-phase entry and maintains S6 kinase activity in T cells responding to IL-2. J Immunol 179:5291-300
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Walsh, Craig M; Luhrs, Keith A; Arechiga, Adrian F (2003) The ""fuzzy logic"" of the death-inducing signaling complex in lymphocytes. J Clin Immunol 23:333-53
Ly, Chi; Arechiga, Adrian F; Melo, Junia V et al. (2003) Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin. Cancer Res 63:5716-22