Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI055556-02
Application #
6798169
Study Section
Special Emphasis Panel (ZRG1-BM-1 (01))
Program Officer
Baker, Phillip J
Project Start
2003-09-15
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$351,000
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390
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Ward, E Sally; Ober, Raimund J (2009) Chapter 4: Multitasking by exploitation of intracellular transport functions the many faces of FcRn. Adv Immunol 103:77-115
Vaccaro, Carlos; Bawdon, Roger; Wanjie, Sylvia et al. (2006) Divergent activities of an engineered antibody in murine and human systems have implications for therapeutic antibodies. Proc Natl Acad Sci U S A 103:18709-14
Zhou, Jinchun; Mateos, Fernando; Ober, Raimund J et al. (2005) Conferring the binding properties of the mouse MHC class I-related receptor, FcRn, onto the human ortholog by sequential rounds of site-directed mutagenesis. J Mol Biol 345:1071-81
Vaccaro, Carlos; Zhou, Jinchun; Ober, Raimund J et al. (2005) Engineering the Fc region of immunoglobulin G to modulate in vivo antibody levels. Nat Biotechnol 23:1283-8