Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI055933-02
Application #
6799982
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Program Officer
Kirkham, Perry M
Project Start
2003-09-15
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$318,863
Indirect Cost
Name
University of Pittsburgh
Department
Pathology
Type
Schools of Medicine
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Marrari, Marilyn; Duquesnoy, Rene J (2010) Detection of donor-specific HLA antibodies before and after removal of a rejected kidney transplant. Transpl Immunol 22:105-9
Duquesnoy, R J; Marrari, M (2009) Correlations between Terasaki's HLA class I epitopes and HLAMatchmaker-defined eplets on HLA-A, -B and -C antigens. Tissue Antigens 74:117-33
Duquesnoy, Rene J; Marrari, Marilyn (2009) HLAMatchmaker-based definition of structural human leukocyte antigen epitopes detected by alloantibodies. Curr Opin Organ Transplant 14:403-9
Marrari, Marilyn; Duquesnoy, Rene J (2009) Why can sensitization by an HLA-DR2 mismatch lead to antibodies that react also with HLA-DR1? Hum Immunol 70:403-9
Marrari, M; Duquesnoy, R J (2009) Correlations between Terasaki's HLA class II epitopes and HLAMatchmaker-defined eplets on HLA-DR and -DQ antigens. Tissue Antigens 74:134-46
Duquesnoy, Rene J; Awadalla, Yehia; Lomago, Jon et al. (2008) Retransplant candidates have donor-specific antibodies that react with structurally defined HLA-DR,DQ,DP epitopes. Transpl Immunol 18:352-60
Duquesnoy, Rene; Spellman, Stephen; Haagenson, Michael et al. (2008) HLAMatchmaker-defined triplet matching is not associated with better survival rates of patients with class I HLA allele mismatched hematopoietic cell transplants from unrelated donors. Biol Blood Marrow Transplant 14:1064-71
Duquesnoy, Rene J; Mostecki, Justin; Hariharan, Jayasree et al. (2008) Structurally based epitope analysis of major histocompatibility complex class I-related chain A (MICA) antibody specificity patterns. Hum Immunol 69:826-32
Duquesnoy, Rene J (2008) Clinical usefulness of HLAMatchmaker in HLA epitope matching for organ transplantation. Curr Opin Immunol 20:594-601
Duquesnoy, Rene J (2008) Structural epitope matching for HLA-alloimmunized thrombocytopenic patients: a new strategy to provide more effective platelet transfusion support? Transfusion 48:221-7

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