Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI056075-02
Application #
6804619
Study Section
Special Emphasis Panel (ZRG1-BM-1 (05))
Program Officer
Schmitt, Clare K
Project Start
2003-09-30
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$304,000
Indirect Cost

  Institution

Name
University of California San Diego
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093

  Publications

Hirata, Yoshihiro; Egea, Laia; Dann, Sara M et al. (2010) GM-CSF-facilitated dendritic cell recruitment and survival govern the intestinal mucosal response to a mouse enteric bacterial pathogen. Cell Host Microbe 7:151-63
Spehlmann, Martina E; Dann, Sara M; Hruz, Petr et al. (2009) CXCR2-dependent mucosal neutrophil influx protects against colitis-associated diarrhea caused by an attaching/effacing lesion-forming bacterial pathogen. J Immunol 183:3332-43
Dann, Sara M; Spehlmann, Martina E; Hammond, Dustin C et al. (2008) IL-6-dependent mucosal protection prevents establishment of a microbial niche for attaching/effacing lesion-forming enteric bacterial pathogens. J Immunol 180:6816-26
Hruz, Petr; Eckmann, Lars (2008) Caspase recruitment domain-containing sensors and adaptors in intestinal innate immunity. Curr Opin Gastroenterol 24:108-14
Greten, Florian R; Arkan, Melek C; Bollrath, Julia et al. (2007) NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. Cell 130:918-31
Dann, Sara M; Eckmann, Lars (2007) Innate immune defenses in the intestinal tract. Curr Opin Gastroenterol 23:115-20
Davids, Barbara J; Palm, J E Daniel; Housley, Michael P et al. (2006) Polymeric immunoglobulin receptor in intestinal immune defense against the lumen-dwelling protozoan parasite Giardia. J Immunol 177:6281-90
Eckmann, Lars (2006) Sensor molecules in intestinal innate immunity against bacterial infections. Curr Opin Gastroenterol 22:95-101
Eckmann, Lars (2006) Animal models of inflammatory bowel disease: lessons from enteric infections. Ann N Y Acad Sci 1072:28-38
Lee, Jongdae; Mo, Ji-Hun; Katakura, Kyoko et al. (2006) Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells. Nat Cell Biol 8:1327-36

Showing the most recent 10 out of 18 publications