Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR026957-10
Application #
2078599
Study Section
Orthopedics and Musculoskeletal Study Section (ORTH)
Project Start
1981-09-30
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1998-08-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Medical Sciences Research Institute
Department
Type
DUNS #
City
Herndon
State
VA
Country
United States
Zip Code
Grainger, David W (2004) Controlled-release and local delivery of therapeutic antibodies. Expert Opin Biol Ther 4:1029-44
Poelstra, Kornelis A; Barekzi, Nazir A; Rediske, Andrea M et al. (2002) Prophylactic treatment of gram-positive and gram-negative abdominal implant infections using locally delivered polyclonal antibodies. J Biomed Mater Res 60:206-15
Barekzi, Nazir A; Felts, Adrian G; Poelstra, Kornelis A et al. (2002) Locally delivered polyclonal antibodies potentiate intravenous antibiotic efficacy against gram-negative infections. Pharm Res 19:1801-7
Poelstra, K A; van der Mei, H C; Gottenbos, B et al. (2000) Pooled human immunoglobulins reduce adhesion of Pseudomonas aeruginosa in a parallel plate flow chamber. J Biomed Mater Res 51:224-32
Felts, A G; Grainger, D W; Slunt, J B (2000) Locally delivered antibodies combined with systemic antibiotics confer synergistic protection against antibiotic-resistant burn wound infection. J Trauma 49:873-8
Rojas, I A; Slunt, J B; Grainger, D W (2000) Polyurethane coatings release bioactive antibodies to reduce bacterial adhesion. J Control Release 63:175-89
Poelstra, K A; Barekzi, N A; Slunt, J B et al. (2000) Surgical irrigation with pooled human immunoglobulin G to reduce post-operative spinal implant infection. Tissue Eng 6:401-11
Felts, A G; Giridhar, G; Grainger, D W et al. (1999) Efficacy of locally delivered polyclonal immunoglobulin against Pseudomonas aeruginosa infection in a murine burn wound model. Burns 25:415-23
Barekzi, N A; Poelstra, K A; Felts, A G et al. (1999) Efficacy of locally delivered polyclonal immunoglobulin against Pseudomonas aeruginosa peritonitis in a murine model. Antimicrob Agents Chemother 43:1609-15
Azizsoltani, E; Myrvik, Q N; Foster, L A et al. (1995) Simple technique for the preparation of silicone gel particles: the effect of silicone gel particles on oxidative responses of macrophages. J Biomed Mater Res 29:101-5

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