Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
2R01AR041206-05
Application #
2080550
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1992-01-03
Project End
2000-12-31
Budget Start
1996-02-20
Budget End
1996-12-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Emory University
Department
Dermatology
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Naik, S M; Cannon, G; Burbach, G J et al. (1999) Human keratinocytes constitutively express interleukin-18 and secrete biologically active interleukin-18 after treatment with pro-inflammatory mediators and dinitrochlorobenzene. J Invest Dermatol 113:766-72
Quinlan, K L; Naik, S M; Cannon, G et al. (1999) Substance P activates coincident NF-AT- and NF-kappa B-dependent adhesion molecule gene expression in microvascular endothelial cells through intracellular calcium mobilization. J Immunol 163:5656-65
Quinlan, K L; Song, I S; Naik, S M et al. (1999) VCAM-1 expression on human dermal microvascular endothelial cells is directly and specifically up-regulated by substance P. J Immunol 162:1656-61
Daneker, G W; Lund, S A; Caughman, S W et al. (1998) Culture and characterization of sinusoidal endothelial cells isolated from human liver. In Vitro Cell Dev Biol Anim 34:370-7
Quinlan, K L; Song, I S; Bunnett, N W et al. (1998) Neuropeptide regulation of human dermal microvascular endothelial cell ICAM-1 expression and function. Am J Physiol 275:C1580-90
Duff, J L; Quinlan, K L; Paxton, L L et al. (1997) Pervanadate mimics IFNgamma-mediated induction of ICAM-1 expression via activation of STAT proteins. J Invest Dermatol 108:295-301
Naik, S M; Shibagaki, N; Li, L J et al. (1997) Interferon gamma-dependent induction of human intercellular adhesion molecule-1 gene expression involves activation of a distinct STAT protein complex. J Biol Chem 272:1283-90
Gille, J; Swerlick, R A; Caughman, S W (1997) Transforming growth factor-alpha-induced transcriptional activation of the vascular permeability factor (VPF/VEGF) gene requires AP-2-dependent DNA binding and transactivation. EMBO J 16:750-9
Baeuml, H; Behrends, U; Peter, R U et al. (1997) Ionizing radiation induces, via generation of reactive oxygen intermediates, intercellular adhesion molecule-1 (ICAM-1) gene transcription and NF kappa B-like binding activity in the ICAM-1 transcriptional regulatory region. Free Radic Res 27:127-42
Paxton, L L; Li, L J; Secor, V et al. (1997) Flanking sequences for the human intercellular adhesion molecule-1 NF-kappaB response element are necessary for tumor necrosis factor alpha-induced gene expression. J Biol Chem 272:15928-35

Showing the most recent 10 out of 15 publications