Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR041808-02
Application #
2080998
Study Section
Biophysical Chemistry Study Section (BBCB)
Project Start
1994-12-01
Project End
1999-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Brandeis University
Department
Type
Organized Research Units
DUNS #
616845814
City
Waltham
State
MA
Country
United States
Zip Code
02454
Himmel, Daniel M; Mui, Suet; O'Neall-Hennessey, Elizabeth et al. (2009) The on-off switch in regulated myosins: different triggers but related mechanisms. J Mol Biol 394:496-505
Himmel, D M; Gourinath, S; Reshetnikova, L et al. (2002) Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor. Proc Natl Acad Sci U S A 99:12645-50
Nyitrai, Miklos; Szent-Gyorgyi, Andrew G; Geeves, Michael A (2002) A kinetic model of the co-operative binding of calcium and ADP to scallop (Argopecten irradians) heavy meromyosin. Biochem J 365:19-30
Szent-Gyorgyi, A G; Kalabokis, V N; Perreault-Micale, C L (1999) Regulation by molluscan myosins. Mol Cell Biochem 190:55-62
Houdusse, A; Kalabokis, V N; Himmel, D et al. (1999) Atomic structure of scallop myosin subfragment S1 complexed with MgADP: a novel conformation of the myosin head. Cell 97:459-70
Dominguez, R; Freyzon, Y; Trybus, K M et al. (1998) Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state. Cell 94:559-71
Cohen, C (1998) Why fibrous proteins are romantic. J Struct Biol 122:3-16
Houdusse, A; Love, M L; Dominguez, R et al. (1997) Structures of four Ca2+-bound troponin C at 2.0 A resolution: further insights into the Ca2+-switch in the calmodulin superfamily. Structure 5:1695-711
Perreault-Micale, C L; Jancso, A; Szent-Gyorgyi, A G (1996) Essential and regulatory light chains of Placopecten striated and catch muscle myosins. J Muscle Res Cell Motil 17:533-42
Houdusse, A; Silver, M; Cohen, C (1996) A model of Ca(2+)-free calmodulin binding to unconventional myosins reveals how calmodulin acts as a regulatory switch. Structure 4:1475-90

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