Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR043468-02
Application #
2083180
Study Section
Arthritis and Musculoskeletal and Skin Diseases Special Grants Review Committee (AMS)
Project Start
1995-04-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Duke University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Wang, Liming; Quarles, L Darryl; Spurney, Robert F (2004) Unmasking the osteoinductive effects of a G-protein-coupled receptor (GPCR) kinase (GRK) inhibitor by treatment with PTH(1-34). J Bone Miner Res 19:1661-70
Quarles, L Darryl (2002) Introduction: emerging therapies derived from the molecular pathogenesis of secondary hyperparathyroidism in ESRD patients. Adv Ren Replace Ther 9:153-8
Spurney, Robert F; Flannery, Patrick J; Garner, Sanford C et al. (2002) Anabolic effects of a G protein-coupled receptor kinase inhibitor expressed in osteoblasts. J Clin Invest 109:1361-71
Liu, Shiguang; Guo, Rong; Tu, Qisheng et al. (2002) Overexpression of Phex in osteoblasts fails to rescue the Hyp mouse phenotype. J Biol Chem 277:3686-97
Xiao, Z S; Liu, S G; Hinson, T K et al. (2001) Characterization of the upstream mouse Cbfa1/Runx2 promoter. J Cell Biochem 82:647-59
Xiao, Z S; Quarles, L D; Chen, Q Q et al. (2001) Effect of asymmetric dimethylarginine on osteoblastic differentiation. Kidney Int 60:1699-704
Liu, S; Guo, R; Quarles, L D (2001) Cloning and characterization of the proximal murine Phex promoter. Endocrinology 142:3987-95
Pi, M; Garner, S C; Flannery, P et al. (2000) Sensing of extracellular cations in CasR-deficient osteoblasts. Evidence for a novel cation-sensing mechanism. J Biol Chem 275:3256-63
Xiao, Z S; Hinson, T K; Quarles, L D (1999) Cbfa1 isoform overexpression upregulates osteocalcin gene expression in non-osteoblastic and pre-osteoblastic cells. J Cell Biochem 74:596-605
Pi, M; Hinson, T K; Quarles, L d (1999) Failure to detect the extracellular calcium-sensing receptor (CasR) in human osteoblast cell lines. J Bone Miner Res 14:1310-9

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