Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Research Project (R01)
Project #
5R01AR043642-02
Application #
2083380
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1995-09-30
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Northwestern University at Chicago
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611

  Publications

Bradley, Kathleen; Scatizzi, John C; Fiore, Stefano et al. (2004) Retinoblastoma suppression of matrix metalloproteinase 1, but not interleukin-6, through a p38-dependent pathway in rheumatoid arthritis synovial fibroblasts. Arthritis Rheum 50:78-87
Perlman, Harris; Bradley, Kathleen; Liu, Hongtao et al. (2003) IL-6 and matrix metalloproteinase-1 are regulated by the cyclin-dependent kinase inhibitor p21 in synovial fibroblasts. J Immunol 170:838-45
Perlman, Harris; Liu, Hongtao; Georganas, Constantinos et al. (2002) Modifications in adenoviral coat fiber proteins and transcriptional regulatory sequences enhance transgene expression. J Rheumatol 29:1593-600
Perlman, H; Pagliari, L J; Nguyen, N et al. (2001) The Fas-FasL death receptor and PI3K pathways independently regulate monocyte homeostasis. Eur J Immunol 31:2421-30
Perlman, H; Liu, H; Georganas, C et al. (2001) Differential expression pattern of the antiapoptotic proteins, Bcl-2 and FLIP, in experimental arthritis. Arthritis Rheum 44:2899-908
Perlman, H; Pagliari, L J; Liu, H et al. (2001) Rheumatoid arthritis synovial macrophages express the Fas-associated death domain-like interleukin-1beta-converting enzyme-inhibitory protein and are refractory to Fas-mediated apoptosis. Arthritis Rheum 44:21-30
Pagliari, L J; Perlman, H; Liu, H et al. (2000) Macrophages require constitutive NF-kappaB activation to maintain A1 expression and mitochondrial homeostasis. Mol Cell Biol 20:8855-65
Georganas, C; Liu, H; Perlman, H et al. (2000) Regulation of IL-6 and IL-8 expression in rheumatoid arthritis synovial fibroblasts: the dominant role for NF-kappa B but not C/EBP beta or c-Jun. J Immunol 165:7199-206
Liu, H; Sidiropoulos, P; Song, G et al. (2000) TNF-alpha gene expression in macrophages: regulation by NF-kappa B is independent of c-Jun or C/EBP beta. J Immunol 164:4277-85
Pope, R; Mungre, S; Liu, H et al. (2000) Regulation of TNF-alpha expression in normal macrophages: the role of C/EBPbeta. Cytokine 12:1171-81

Showing the most recent 10 out of 14 publications