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Springer, James B; Colvin, O Michael; Ludeman, Susan M (2014) Labeled oxazaphosphorines for applications in mass spectrometry studies. 2. Synthesis of deuterium-labeled 2-dechloroethylcyclophosphamides and 2- and 3-dechloroethylifosfamides. J Labelled Comp Radiopharm 57:110-4
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Pinto, N; Gamazon, E R; Antao, N et al. (2014) Integrating cell-based and clinical genome-wide studies to identify genetic variants contributing to treatment failure in neuroblastoma patients. Clin Pharmacol Ther 95:644-52
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Gamcsik, Michael P; Clark, M Daniel; Ludeman, Susan M et al. (2011) Non-invasive monitoring of L-2-oxothiazolidine-4-carboxylate metabolism in the rat brain by in vivo 13C magnetic resonance spectroscopy. Neurochem Res 36:443-51
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Hlavin, Erica M; Smeaton, Michael B; Noronha, Anne M et al. (2010) Cross-link structure affects replication-independent DNA interstrand cross-link repair in mammalian cells. Biochemistry 49:3977-88
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Pinto, Navin; Ludeman, Susan M; Dolan, M Eileen (2009) Drug focus: Pharmacogenetic studies related to cyclophosphamide-based therapy. Pharmacogenomics 10:1897-903
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Emmenegger, Urban; Shaked, Yuval; Man, Shan et al. (2007) Pharmacodynamic and pharmacokinetic study of chronic low-dose metronomic cyclophosphamide therapy in mice. Mol Cancer Ther 6:2280-9
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Spasojevic, Ivan; Colvin, O Michael; Warshany, Keith R et al. (2006) New approach to the activation of anti-cancer pro-drugs by metalloporphyrin-based cytochrome P450 mimics in all-aqueous biologically relevant system. J Inorg Biochem 100:1897-902
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Springer, James B; Chang, Young H; Koo, Kyo I et al. (2004) 1,3- vs 1,5-intramolecular alkylation reactions in isophosphoramide and phosphoramide mustards. Chem Res Toxicol 17:1217-26
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Smith, Sonali M; Ludeman, Susan M; Wilson, Lynette R et al. (2003) Selective enhancement of ifosfamide-induced toxicity in Chinese hamster ovary cells. Cancer Chemother Pharmacol 52:291-302
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Ludeman, Susan M; Gamcsik, Michael P (2002) Mechanisms of resistance against cyclophosphamide and ifosfamide: can they be overcome without sacrificing selectivity? Cancer Treat Res 112:177-97
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