Three basic lines of investigation pertaining to the control of erythroid differentiation of murine erythroleukemia cells will be investigated. The molecular processes that are responsible for the commitment of these cells to terminal erythroid differentiation will be studied. The relationship between globin mRNA synthesis and commitment will be analyzed. The control of genes expressed during the terminal phase of the program will also be studied. (M)

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA017575-13
Application #
3164737
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1978-05-01
Project End
1988-04-30
Budget Start
1987-05-01
Budget End
1988-04-30
Support Year
13
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Type
Organized Research Units
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139
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