Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA027578-15
Application #
2087612
Study Section
Virology Study Section (VR)
Project Start
1980-05-01
Project End
1997-04-30
Budget Start
1995-05-01
Budget End
1997-04-30
Support Year
15
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Virginia
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Huff, J L; Jelinek, M A; Jamieson, T A et al. (1996) Expression and maturation of the cellular sea receptor, a member of the hepatocyte growth factor (HGF) receptor family of protein tyrosine kinases. Oncogene 12:299-307
Huff, J L; Jelinek, M A; Borgman, C A et al. (1993) The protooncogene c-sea encodes a transmembrane protein-tyrosine kinase related to the Met/hepatocyte growth factor/scatter factor receptor. Proc Natl Acad Sci U S A 90:6140-4
Biegalke, B J; Heaney, M L; Bouton, A et al. (1987) MC29 deletion mutants which fail to transform chicken macrophages are competent for transformation of quail macrophages. J Virol 61:2138-42
Raymond, V W; Parsons, J T (1987) Identification of an amino terminal domain required for the transforming activity of the Rous sarcoma virus src protein. Virology 160:400-10
Parsons, J T; Wilkerson, V; Parsons, S J (1986) Structural and functional motifs of the Rous sarcoma virus src protein. Gene Amplif Anal 4:1-19
Heaney, M L; Pierce, J; Parsons, J T (1986) Site-directed mutagenesis of the gag-myc gene of avian myelocytomatosis virus 29: biological activity and intracellular localization of structurally altered proteins. J Virol 60:167-76
Morgan, J H; Parsons, J T (1986) Characterization of c-myc proteins from avian bursal lymphoma cell lines. Virology 150:178-86
Parsons, S J; McCarley, D J; Raymond, V W et al. (1986) Localization of conserved and nonconserved epitopes within the Rous sarcoma virus-encoded src protein. J Virol 59:755-8
Wilkerson, V W; Bryant, D L; Parsons, J T (1985) Rous sarcoma virus variants that encode src proteins with an altered carboxy terminus are defective for cellular transformation. J Virol 55:314-21
Morgan, J H; Papas, T S; Parsons, J T (1985) Isolation of antibodies specific for avian viral and cellular myc proteins. J Natl Cancer Inst 75:937-47