Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA032146-11
Application #
2088303
Study Section
Medical Biochemistry Study Section (MEDB)
Project Start
1983-02-01
Project End
1997-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Pediatrics
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
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Melhem, R; Hailat, N; Kuick, R et al. (1997) Quantitative analysis of Op18 phosphorylation in childhood acute leukemia. Leukemia 11:1690-5
Chang, C L; Strahler, J R; Thoraval, D H et al. (1996) A nucleoside diphosphate kinase A (nm23-H1) serine 120-->glycine substitution in advanced stage neuroblastoma affects enzyme stability and alters protein-protein interaction. Oncogene 12:659-67
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Keim, D R; Hailat, N; Kuick, R et al. (1993) PCNA levels in neuroblastoma are increased in tumors with an amplified N-myc gene and in metastatic stage tumors. Clin Exp Metastasis 11:83-90
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Wang, Y K; Liao, P C; Allison, J et al. (1993) Phorbol 12-myristate 13-acetate-induced phosphorylation of Op18 in Jurkat T cells. Identification of phosphorylation sites by matrix-assisted laser desorption ionization mass spectrometry. J Biol Chem 268:14269-77
Hanash, S M; Beretta, L; Barcroft, C L et al. (1993) Mapping of the gene for interferon-inducible dsRNA-dependent protein kinase to chromosome region 2p21-22: a site of rearrangements in myeloproliferative disorders. Genes Chromosomes Cancer 8:34-7
Hanash, S M; Strahler, J R; Chan, Y et al. (1993) Data base analysis of protein expression patterns during T-cell ontogeny and activation. Proc Natl Acad Sci U S A 90:3314-8
Strahler, J R; Hailat, N; Lamb, B J et al. (1992) Activation of resting peripheral blood lymphocytes through the T cell receptor induces rapid phosphorylation of Op18. J Immunol 149:1191-8

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