Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA032516-03S2
Application #
3170415
Study Section
(SSS)
Project Start
1982-09-15
Project End
1986-02-28
Budget Start
1984-09-01
Budget End
1986-02-28
Support Year
3
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
Muench, M O; Firpo, M T; Moore, M A (1993) Bone marrow transplantation with interleukin-1 plus kit-ligand ex vivo expanded bone marrow accelerates hematopoietic reconstitution in mice without the loss of stem cell lineage and proliferative potential. Blood 81:3463-73
Muench, M O; Gasparetto, C; Moore, M A (1992) The in vitro growth of murine high proliferative potential-colony forming cells is not enhanced by growth in a low oxygen atmosphere. Cytokine 4:488-94
Muench, M O; Guy, Z; Moore, M A (1992) Ex vivo differentiation therapy as a method of leukemic cell purging in murine bone marrow expansion cultures. Cancer Res 52:6576-82
Muench, M O; Schneider, J G; Moore, M A (1992) Interactions among colony-stimulating factors, IL-1 beta, IL-6, and kit-ligand in the regulation of primitive murine hematopoietic cells. Exp Hematol 20:339-49
Muench, M O; Moore, M A (1992) Accelerated recovery of peripheral blood cell counts in mice transplanted with in vitro cytokine-expanded hematopoietic progenitors. Exp Hematol 20:611-8
Steffen, M; Budde-Steffen, C; Gabrilove, J L et al. (1992) Modulation of leukemic cell growth by tumor necrosis factor: action and expression in myeloid leukemia. Leukemia 6:634-41
Moore, M A (1991) The future of cytokine combination therapy. Cancer 67:2718-26
Moore, M A (1991) Review: Stratton Lecture 1990. Clinical implications of positive and negative hematopoietic stem cell regulators. Blood 78:1-19
Slordal, L; Warren, D J; Moore, M A (1990) Protective effects of tumor necrosis factor on murine hematopoiesis during cycle-specific cytotoxic chemotherapy. Cancer Res 50:4216-20
Warren, D J; Slordal, L; Moore, M A (1990) Tumor-necrosis factor induces cell cycle arrest in multipotential hematopoietic stem cells: a possible radioprotective mechanism. Eur J Haematol 45:158-63

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