Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA037912-09S1
Application #
2089471
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1984-08-01
Project End
1997-04-30
Budget Start
1994-05-01
Budget End
1995-04-30
Support Year
9
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Type
Organized Research Units
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Gomez, G; Clarkin, K Z; Kraig, E et al. (2000) TCR v(beta) repertoire restriction and lack of CDR3 conservation implicate TCR-superantigen interactions in promoting the clonal evolution of murine thymic lymphomas. Int Immunol 12:263-70
Richie, E R; Walker, D A (2000) Production and characterization of immature murine T-lymphoma cell lines. Methods Mol Biol 134:177-84
Robles, A I; Larcher, F; Whalin, R B et al. (1996) Expression of cyclin D1 in epithelial tissues of transgenic mice results in epidermal hyperproliferation and severe thymic hyperplasia. Proc Natl Acad Sci U S A 93:7634-8
Richie, E R; Angel, J M; Rinchik, E M (1996) Tlag1, a novel murine tumor susceptibility gene that regulates MNU-induced thymic lymphoma development. Prog Clin Biol Res 395:23-32
Poetschke, H L; Klug, D B; Walker, D et al. (1996) Cross-linking the TCR complex induces apoptosis in CD4+8+ thymocytes in the presence of cyclosporin A. Dev Immunol 5:1-15
Romach, E; Moore, J; Rummel, S et al. (1994) Influence of sex and carcinogen treatment protocol on tumor latency and frequency of K-ras mutations in N-methyl-N-nitrosourea-induced lymphomas. Carcinogenesis 15:2275-80
Richie, E R; McEntire, B B; Coghlan, L et al. (1991) Murine T-lymphomas corresponding to the immature CD4-8+ thymocyte subset. Dev Immunol 1:255-63
Stettner, S L; Rummel, S A; Conti, C J et al. (1991) N-methyl-N-nitrosourea alters thymocyte subset distribution and targets immature CD4-8+ cells for lymphoma development. Cancer Res 51:737-40
Richie, E R; Angel, J M; Cloyd, M W (1991) Influence of murine leukemia proviral integrations on development of N-methyl-N-nitrosourea-induced thymic lymphomas in AKR mice. J Virol 65:5751-6
Nairn, R S; McIntyre, B W; Richie, E R et al. (1989) Characterization of env gene recombination in x-ray--induced thymomas of C57BL/6 mice. Mol Carcinog 2:126-30

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