Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA039417-06S1
Application #
3178357
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1988-07-01
Project End
1994-08-31
Budget Start
1991-09-30
Budget End
1992-08-31
Support Year
6
Fiscal Year
1992
Total Cost
Indirect Cost
Name
International Agency for Research on Cancer
Department
Type
DUNS #
279551881
City
Lyon
State
Country
France
Zip Code
69008
Bingham, S A; Pignatelli, B; Pollock, J R et al. (1996) Does increased endogenous formation of N-nitroso compounds in the human colon explain the association between red meat and colon cancer? Carcinogenesis 17:515-23
Alexakis, T; Boadi, D K; Quong, D et al. (1995) Microencapsulation of DNA within alginate microspheres and crosslinked chitosan membranes for in vivo application. Appl Biochem Biotechnol 50:93-106
O'Neill, I; Bingham, S; Ellul, A et al. (1993) Magnetic microcapsule exploration in the gastrointestinal cavity of the origins of colorectal cancer-associated DNA-damaging agents in the human diet. Environ Health Perspect 99:161-7
O'Neill, I; Ridgway, O; Ellul, A et al. (1993) Gastrointestinal monitoring of DNA-damaging agents with magnetic microcapsules. Mutat Res 290:127-38
Rumney, C J; Rowland, I R; Coutts, T M et al. (1993) Effects of risk-associated human dietary macrocomponents on processes related to carcinogenesis in human-flora-associated (HFA) rats. Carcinogenesis 14:79-84
O'Neill, I (1993) Reactive microcapsules for detection of carcinogen sources in the gut. J Microencapsul 10:283-308
Bingham, S A; Ellul, A; Cummings, J H et al. (1992) Novel detection by magnetic microcapsules in the human gastrointestinal tract of cross-linking agents and diet-dependent reactive oxygen species. Carcinogenesis 13:683-90
O'Neill, I; Ohgaki, H; Ellul, A et al. (1992) Entrapment by magnetic microcapsules of the protein pyrolysates IQ, PhIP and Glu-P-1, and alteration of IQ metabolite exposure within the rat gastrointestinal tract by risk-modulating components of the human diet. Carcinogenesis 13:2353-9
O'Neill, I K; Goldberg, M T; el Ghissassi, F et al. (1991) Dietary fibre, fat and beef modulation of colonic nuclear aberrations and microcapsule-trapped gastrointestinal metabolites of benzo[a]pyrene-treated C57/B6 mice consuming human diets. Carcinogenesis 12:175-80
Ellul, A; Povey, A; O'Neill, I K (1990) Presence of endogenous cross-linking/bifunctional agents in gastrointestinal cavity as detected by transit of magnetic PEI microcapsules. Carcinogenesis 11:1577-82

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