Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA042070-05
Application #
3182876
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1986-04-01
Project End
1990-09-14
Budget Start
1990-04-01
Budget End
1990-09-14
Support Year
5
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of South Florida
Department
Type
Schools of Medicine
DUNS #
City
Tampa
State
FL
Country
United States
Zip Code
33612
Cory, A H; Hertel, L W; Kroin, J S et al. (1993) Effects of 2',2'-difluorodeoxycytidine (Gemcitabine) on wild type and variant mouse leukemia L1210 cells. Oncol Res 5:59-63
Cory, J G; Cory, A H; Raber, N K et al. (1993) Structural aspects of N-hydroxy-N'-aminoguanidine derivatives as inhibitors of L1210 cell growth and ribonucleotide reductase activity. Adv Enzyme Regul 33:129-40
Carter, G L; Cory, J G (1992) Factors affecting the mRNA levels for the non-heme iron and effector-binding subunits of ribonucleotide reductase. Adv Enzyme Regul 32:227-40
Cory, J G; Cory, A H; Long, S D et al. (1992) Altered steady-state levels of the messenger RNAs for c-myc and p53 in L1210 cell lines resistant to deoxyadenosine. Cancer Res 52:2000-3
Johnson, C E; Hughes, K; Cory, J G (1991) Cell-cycle associated transcriptional regulation of ribonucleotide reductase in L1210 leukemia cells and drug-resistant variants. Cancer Commun 3:341-9
Matsumoto, M; Rey, D A; Cory, J G (1990) Effects of cytosine arabinoside and hydroxyurea on the synthesis of deoxyribonucleotides and DNA replication in L1210 cells. Adv Enzyme Regul 30:47-59
Thompson, D P; Carter, G L; Cory, J G (1989) Changes in messenger RNA levels for the subunits of ribonucleotide reductase during the cell cycle of leukemia L1210 cells. Cancer Commun 1:253-60
Carter, G L; Cory, J G (1989) Selective resistance of L1210 cell lines to inhibitors directed at the subunits of ribonucleotide reductase. Adv Enzyme Regul 29:123-39
Carter, G L; Thompson, D P; Cory, J G (1989) Mechanisms of drug resistance to inhibitors directed at the individual subunits of ribonucleotide reductase. Cancer Commun 1:13-20
Carter, G L; Cory, J G (1988) Cross-resistance patterns in hydroxyurea-resistant leukemia L1210 cells. Cancer Res 48:5796-9

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