Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA056434-04
Application #
2097311
Study Section
Special Emphasis Panel (SRC (40))
Project Start
1992-06-01
Project End
1998-05-31
Budget Start
1995-08-10
Budget End
1998-05-31
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Texas Medical Br Galveston
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
041367053
City
Galveston
State
TX
Country
United States
Zip Code
77555
Schwartz, J L; Jordan, R; Sun, J et al. (2000) Dose-dependent changes in the spectrum of mutations induced by ionizing radiation. Radiat Res 153:312-7
An, J; Trieff, N M; Hsie, A W (1998) PCR-directed DNA sequencing of ""nondeletion"" HPRT-mutants induced by bleomycin in CHO K1-BH4 cells. Environ Mol Mutagen 32:244-50
Schwartz, J L; Hsie, A W (1997) Genetic and cytogenetic markers of exposure to high-linear energy transfer radiation. Radiat Res 148:S87-92
Hsie, A W; Porter, R C; Xu, Z et al. (1996) Molecular markers of ionizing radiation-induced gene mutations in mammalian cells. Environ Health Perspect 104 Suppl 3:675-8
Schwartz, J L; Porter, R C; Hsie, A W (1996) The molecular nature of spontaneous mutations at the hprt locus in the radiosensitive CHO mutant xrs-5. Mutat Res 351:53-60
Xu, Z; Yu, Y; Schwartz, J L et al. (1995) Molecular nature of spontaneous mutations at the hypoxanthine-guanine phosphoribosyltransferase (hprt) locus in Chinese hamster ovary cells. Environ Mol Mutagen 26:127-38
An, J; Hsie, A W (1994) Polymerase chain reaction-directed DNA sequencing of bleomycin-induced ""nondeletion""-type, 6-thioguanine-resistant mutants in Chinese hamster ovary cell derivative AS52: effects of an inhibitor and a mimic of superoxide dismutase. Environ Mol Mutagen 23:101-9
Yu, Y; Xu, Z; Hsie, A W (1994) Adriamycin induces large deletions as a major type of mutation in CHO cells. Mutat Res 325:91-8
Schwartz, J L; Rotmensch, J; Sun, J et al. (1994) Multiplex polymerase chain reaction-based deletion analysis of spontaneous, gamma ray- and alpha-induced hprt mutants of CHO-K1 cells. Mutagenesis 9:537-40