Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA056881-01S1
Application #
3201301
Study Section
Pathology B Study Section (PTHB)
Project Start
1992-08-05
Project End
1997-07-31
Budget Start
1992-08-05
Budget End
1993-07-31
Support Year
1
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
Buzin, C H; Tang, S H; Cunningham, J M et al. (2001) Low frequency of p53 gene mutations in breast cancers of Japanese-American women. Nutr Cancer 39:72-7
Blaszyk, H; Hartmann, A; Cunningham, J M et al. (2000) A prospective trial of midwest breast cancer patients: a p53 gene mutation is the most important predictor of adverse outcome. Int J Cancer 89:32-8
Hartmann, A; Blaszyk, H; Kovach, J S et al. (1997) The molecular epidemiology of p53 gene mutations in human breast cancer. Trends Genet 13:27-33
Hartmann, A; Blaszyk, H; Saitoh, S et al. (1996) High frequency of p53 gene mutations in primary breast cancers in Japanese women, a low-incidence population. Br J Cancer 73:896-901
Kovach, J S; Hartmann, A; Blaszyk, H et al. (1996) Mutation detection by highly sensitive methods indicates that p53 gene mutations in breast cancer can have important prognostic value. Proc Natl Acad Sci U S A 93:1093-6
Blaszyk, H; Hartmann, A; Tamura, Y et al. (1996) Molecular epidemiology of breast cancers in northern and southern Japan: the frequency, clustering, and patterns of p53 gene mutations differ among these two low-risk populations. Oncogene 13:2159-66
Hartmann, A; Blaszyk, H; McGovern, R M et al. (1995) p53 gene mutations inside and outside of exons 5-8: the patterns differ in breast and other cancers. Oncogene 10:681-8
Hartmann, A; Rosanelli, G; Blaszyk, H et al. (1995) Novel pattern of P53 mutation in breast cancers from Austrian women. J Clin Invest 95:686-9
Blaszyk, H; Hartmann, A; Schroeder, J J et al. (1995) Rapid and efficient screening for p53 gene mutations by dideoxy fingerprinting. Biotechniques 18:256-60
Saitoh, S; Cunningham, J; De Vries, E M et al. (1994) p53 gene mutations in breast cancers in midwestern US women: null as well as missense-type mutations are associated with poor prognosis. Oncogene 9:2869-75

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