Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA057322-02
Application #
2098056
Study Section
Pathology B Study Section (PTHB)
Project Start
1995-06-01
Project End
1996-10-31
Budget Start
1996-06-01
Budget End
1996-10-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Thomas Jefferson University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Fortson, Wendell S; Kayarthodi, Shubhalaxmi; Fujimura, Yasuo et al. (2011) Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells. Int J Oncol 39:111-9
Maniccia, Anna W; Lewis, Catherine; Begum, Nurjahan et al. (2009) Mitochondrial localization, ELK-1 transcriptional regulation and growth inhibitory functions of BRCA1, BRCA1a, and BRCA1b proteins. J Cell Physiol 219:634-41
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Chai, Y; Chipitsyna, G; Cui, J et al. (2001) c-Fos oncogene regulator Elk-1 interacts with BRCA1 splice variants BRCA1a/1b and enhances BRCA1a/1b-mediated growth suppression in breast cancer cells. Oncogene 20:1357-67
Fujimura, Y; Siddique, H; Lee, L et al. (2001) EWS-ATF-1 chimeric protein in soft tissue clear cell sarcoma associates with CREB-binding protein and interferes with p53-mediated trans-activation function. Oncogene 20:6653-9
Chai, Y L; Cui, J; Shao, N et al. (1999) The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter. Oncogene 18:263-8
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Shao, N; Chai, Y; Cui, J Q et al. (1998) Induction of apoptosis by Elk-1 and deltaElk-1 proteins. Oncogene 17:527-32
Cui, J Q; Shao, N; Chai, Y et al. (1998) BRCA1 splice variants BRCA1a and BRCA1b associate with CBP co-activator. Oncol Rep 5:591-5
Cui, J Q; Wang, H; Reddy, E S et al. (1998) Differential transcriptional activation by the N-terminal region of BRCA1 splice variants BRCA1a and BRCA1b. Oncol Rep 5:585-9

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