Mechanisms for Oxidative Stress-Induced Apoptosis

Held, Kathryn Dale

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 5R01CA063997-05
• Application #: 6376072
• Study Section: Special Emphasis Panel (ZRG1-MEP (02))
• Program Officer: Yang, Shen K
• Project Start: 1997-04-10
• Project End: 2003-03-31
• Budget Start: 2001-04-01
• Budget End: 2002-03-31
• Support Year: 5
• Fiscal Year: 2001
• Total Cost: $272,475

Institution

• Name: Massachusetts General Hospital
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02199

Publications

Biaglow, J E; Donahue, J; Tuttle, S et al. (2000) A method for measuring disulfide reduction by cultured mammalian cells: relative contributions of glutathione-dependent and glutathione-independent mechanisms. Anal Biochem 281:77-86

Tartier, L; McCarey, Y L; Biaglow, J E et al. (2000) Apoptosis induced by dithiothreitol in HL-60 cells shows early activation of caspase 3 and is independent of mitochondria. Cell Death Differ 7:1002-10

Manevich, Y; Held, K D; Biaglow, J E (1997) Coumarin-3-carboxylic acid as a detector for hydroxyl radicals generated chemically and by gamma radiation. Radiat Res 148:580-91