Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA065675-02
Application #
2108756
Study Section
Metabolic Pathology Study Section (MEP)
Project Start
1995-09-27
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Allegheny University of Health Sciences
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19129
Albo, D; Rothman, V L; Roberts, D D et al. (2000) Tumour cell thrombospondin-1 regulates tumour cell adhesion and invasion through the urokinase plasminogen activator receptor. Br J Cancer 83:298-306
Albo, D; Berger, D H; Vogel, J et al. (1999) Thrombospondin-1 and transforming growth factor beta-1 upregulate plasminogen activator inhibitor type 1 in pancreatic cancer. J Gastrointest Surg 3:411-7
Albo, D; Berger, D H; Rothman, V L et al. (1999) Role of urokinase plasminogen activator receptor in thrombospondin 1-mediated tumor cell invasion. J Surg Res 82:331-8
Roth, J J; Sung, J J; Granick, M S et al. (1999) Thrombospondin 1 and its specific cysteine-serine-valine-threonine-cysteine-clycine receptor in fetal wounds. Ann Plast Surg 42:553-63
Roth, J J; Albo, D; Rothman, V L et al. (1998) Thrombospondin-1 and its CSVTCG-specific receptor in wound healing and cancer. Ann Plast Surg 40:494-501
Albo, D; Berger, D H; Tuszynski, G P (1998) The effect of thrombospondin-1 and TGF-beta 1 on pancreatic cancer cell invasion. J Surg Res 76:86-90
Qian, X; Wang, T N; Rothman, V L et al. (1997) Thrombospondin-1 modulates angiogenesis in vitro by up-regulation of matrix metalloproteinase-9 in endothelial cells. Exp Cell Res 235:403-12
Albo, D; Berger, D H; Wang, T N et al. (1997) Thrombospondin-1 and transforming growth factor-beta l promote breast tumor cell invasion through up-regulation of the plasminogen/plasmin system. Surgery 122:493-9; discussion 499-500
Tuszynski, G P; Wang, T N; Berger, D (1997) Adhesive proteins and the hematogenous spread of cancer. Acta Haematol 97:29-39
Roth, J J; Reiver, D M; Granick, M S et al. (1997) Histopathology and clinical assessment correlate with the cysteine-serine-valine-threonine-cysteine-glycine (CSVTCG) receptor of thrombospondin-1 in breast tumors. Histol Histopathol 12:1013-8

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