Hormonal and Zinc Regulation of Prostate M-Aconitase

Costello, Leslie C.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 1R01CA071207-01
• Application #: 2114900
• Study Section: Special Emphasis Panel (ZRG2-REB (01))
• Project Start: 1996-06-01
• Project End: 2000-03-31
• Budget Start: 1996-06-01
• Budget End: 1997-03-31
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: University of Maryland Baltimore
• Department: Physiology
• Type: Schools of Dentistry
• DUNS #: 003255213
• City: Baltimore
• State: MD
• Country: United States
• Zip Code: 21201

Publications

Franklin, Renty B; Zou, Jing; Zheng, Yao et al. (2016) Zinc Ionophore (Clioquinol) Inhibition of Human ZIP1-Deficient Prostate Tumor Growth in the Mouse Ectopic Xenograft Model: A Zinc Approach for the Efficacious Treatment of Prostate Cancer. Int J Cancer Clin Res 3:

Costello, Leslie C; Franklin, Renty B; Reynolds, Mark A et al. (2012) The Important Role of Osteoblasts and Citrate Production in Bone Formation: ""Osteoblast Citration"" as a New Concept for an Old Relationship. Open Bone J 4:

Costello, Leslie C; Zou, Jing; Desouki, Mohamed Mokhtar et al. (2012) Evidence for changes in RREB-1, ZIP3, and Zinc in the early development of pancreatic adenocarcinoma. J Gastrointest Cancer 43:570-8

Franklin, Renty B; Levy, Bernard A; Zou, Jing et al. (2012) ZIP14 zinc transporter downregulation and zinc depletion in the development and progression of hepatocellular cancer. J Gastrointest Cancer 43:249-57

Costello, Leslie C; Franklin, Renty B (2012) Cytotoxic/tumor suppressor role of zinc for the treatment of cancer: an enigma and an opportunity. Expert Rev Anticancer Ther 12:121-8

Costello, Leslie C; Franklin, Renty B (2011) Integration of molecular genetics and proteomics with cell metabolism: how to proceed; how not to proceed! Gene 486:88-93

Costello, Leslie C; Franklin, Renty B (2011) Zinc is decreased in prostate cancer: an established relationship of prostate cancer! J Biol Inorg Chem 16:3-8

Costello, Leslie C; Fenselau, Catherine C; Franklin, Renty B (2011) Evidence for operation of the direct zinc ligand exchange mechanism for trafficking, transport, and reactivity of zinc in mammalian cells. J Inorg Biochem 105:589-99

Costello, L C; Franklin, R B (2009) Prostatic fluid electrolyte composition for the screening of prostate cancer: a potential solution to a major problem. Prostate Cancer Prostatic Dis 12:17-24

Franklin, Renty B; Costello, Leslie C (2009) The important role of the apoptotic effects of zinc in the development of cancers. J Cell Biochem 106:750-7