This application requests a five-year renewal of our project entitled """"""""The Quality of Life of Older Adult Long-term Cancer Survivors"""""""" (R01-CA78975), originally funded as a five-year, longitudinal study. The primary aim is to determine the long-term (5 or more years post-treatment) physiological, psychological, social, and spiritual effects of surviving cancer on older adults (age 60+). This competing renewal responds to the NIA's (Yancik at al., 2001) and the NCI's (Meadows et al., 1998) reports that call for long-term follow-up of older cancer survivors. A comprehensive cancer survivorship model focusing on quality of life (QOL) is framed in the stress and coping perspective. Physical health QOL outcomes include health appraisal, physical and cognitive functioning, and disability burden. Important aims are to distinguish the effects of cancer and its treatment from those of other co-morbid health problems and to document trajectories in health effects and their causes. Psychological outcomes include psychological distress (e.g., anxiety and depression), PTSD symptoms, cancer-related health worries, life satisfaction, and post-traumatic growth. Social outcomes include identity relevant characteristics such as self-esteem, body image, survivor identity, and the ability to maintain valued roles and activities. Spiritual outcomes include religious and spiritual activities and life purpose. The model includes ameliorative resources such as coping style, health beliefs, health promotion, and marshalling health care support. The proposed renewal study will include 320 survivors who have been treated at the Ireland Cancer Center of University Hospitals Health System of Cleveland, an NIH Clinical Cancer Center. The sample will continue to be stratified to include survivors of the most common survivable cancers among older adults, colorectal, prostate, and breast cancers, allowing for the examination of gender differences in the context of gender common and gender specific cancers. African-Americans will continue to be over-sampled to provide the analytic power to identify racial differences in response to cancer. In addition to three annual waves of interviews, event response interviews will document the effects of significant health/illness changes or personal/social losses that occur between annual interviews and identify the transitory/episodic effects of these changes. Analysis will include multivariate analysis such as regression, structural equation modeling, and growth curve analysis. Specific comparative analyses are planned with age, gender, racial, and cancer type subgroups.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA078975-07
Application #
6781808
Study Section
Special Emphasis Panel (ZRG1-SNEM-4 (01))
Program Officer
Aziz, Noreen M
Project Start
1998-09-18
Project End
2008-07-31
Budget Start
2004-08-01
Budget End
2005-07-31
Support Year
7
Fiscal Year
2004
Total Cost
$323,595
Indirect Cost
Name
Case Western Reserve University
Department
Social Sciences
Type
Schools of Arts and Sciences
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Deimling, Gary T; Albitz, Casey; Monnin, Kara et al. (2017) Personality and psychological distress among older adult, long-term cancer survivors. J Psychosoc Oncol 35:17-31
Kahana, Boaz; Kahana, Eva; Deimling, Gary et al. (2011) Determinants of altered life perspectives among older-adult long-term cancer survivors. Cancer Nurs 34:209-18
Bowman, Karen F; Rose, Julia H; Deimling, Gary T et al. (2010) Primary care physicians' involvement in the cancer care of older long-term survivors. J Aging Health 22:673-86
Deimling, Gary T; Bowman, Karen F; Wagner, Louis J (2007) Cancer survivorship and identity among long-term survivors. Cancer Invest 25:758-65
Deimling, Gary T; Sterns, Samantha; Bowman, Karen F et al. (2007) Functioning and activity participation restrictions among older adult, long-term cancer survivors. Cancer Invest 25:106-16
Bowman, Karen F; Rose, Julia H; Deimling, Gary T (2006) Appraisal of the cancer experience by family members and survivors in long-term survivorship. Psychooncology 15:834-45
Deimling, Gary T; Bowman, Karen F; Sterns, Samantha et al. (2006) Cancer-related health worries and psychological distress among older adult, long-term cancer survivors. Psychooncology 15:306-20
Deimling, Gary T; Wagner, Louis J; Bowman, Karen F et al. (2006) Coping among older-adult, long-term cancer survivors. Psychooncology 15:143-59
Deimling, Gary T; Sterns, Samantha; Bowman, Karen F et al. (2005) The health of older-adult, long-term cancer survivors. Cancer Nurs 28:415-24
Bowman, Karen F; Rose, Julia H; Deimling, Gary T (2005) Families of long-term cancer survivors: health maintenance advocacy and practice. Psychooncology 14:1008-17

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