Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA082858-03S1
Application #
6415635
Study Section
Metabolic Pathology Study Section (MEP)
Program Officer
Rosenfeld, Bobby
Project Start
1999-07-01
Project End
2004-04-30
Budget Start
2001-05-01
Budget End
2002-04-30
Support Year
3
Fiscal Year
2001
Total Cost
$42,920
Indirect Cost
Name
Cleveland Clinic Lerner
Department
Type
DUNS #
017730458
City
Cleveland
State
OH
Country
United States
Zip Code
44195
Crosby, M E; Jacobberger, J; Gupta, D et al. (2007) E2F4 regulates a stable G2 arrest response to genotoxic stress in prostate carcinoma. Oncogene 26:1897-909
Mazumder, Suparna; Plesca, Dragos; Kinter, Michael et al. (2007) Interaction of a cyclin E fragment with Ku70 regulates Bax-mediated apoptosis. Mol Cell Biol 27:3511-20
Oancea, Marcela; Mazumder, Suparna; Crosby, Meredith E et al. (2006) Apoptosis assays. Methods Mol Med 129:279-90
Bucur, Octavian; Ray, Subrata; Bucur, Maria Cristina et al. (2006) APO2 ligand/tumor necrosis factor-related apoptosis-inducing ligand in prostate cancer therapy. Front Biosci 11:1549-68
Ray, S; Bucur, O; Almasan, A (2005) Sensitization of prostate carcinoma cells to Apo2L/TRAIL by a Bcl-2 family protein inhibitor. Apoptosis 10:1411-8
Zheng, Yanhua; Shi, Yong; Tian, Changhai et al. (2004) Essential role of the voltage-dependent anion channel (VDAC) in mitochondrial permeability transition pore opening and cytochrome c release induced by arsenic trioxide. Oncogene 23:1239-47
Oancea, Marcela; Mani, Aruna; Hussein, Mohamad A et al. (2004) Apoptosis of multiple myeloma. Int J Hematol 80:224-31
DuPree, Erica L; Mazumder, Suparna; Almasan, Alexandru (2004) Genotoxic stress induces expression of E2F4, leading to its association with p130 in prostate carcinoma cells. Cancer Res 64:4390-3
Mazumder, S; DuPree, E L; Almasan, A (2004) A dual role of cyclin E in cell proliferation and apoptosis may provide a target for cancer therapy. Curr Cancer Drug Targets 4:65-75
Crosby, Meredith E; Oancea, Marcela; Almasan, Alex (2004) p53 binding to target sites is dynamically regulated before and after ionizing radiation-mediated DNA damage. J Environ Pathol Toxicol Oncol 23:67-79

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